Visão selecionada em Inglês
| Descritor em português: | Proteínas de Checkpoint Imunológico | ||||||
| Descritor em inglês: | Immune Checkpoint Proteins | ||||||
| Descritor em espanhol: |
Proteínas de Punto de Control Inmunitario
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| Descritor em francês: | Protéines de points de contrôle immunitaires | ||||||
| Termo(s) alternativo(s): |
Checkpoint Molecule, Immune Checkpoint Molecule, Inhibitory Checkpoint Molecule, Stimulatory Checkpoint Protein, Immune Immune Checkpoint Molecule Immune Checkpoint Molecules Immune Checkpoint Protein Inhibitory Checkpoint Molecule Inhibitory Checkpoint Molecules Molecule, Immune Checkpoint Protein, Immune Checkpoint Stimulatory Checkpoint Molecule Stimulatory Checkpoint Molecules |
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| Código(s) hierárquico(s): |
D12.776.465 D23.383 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000082102 | ||||||
| Nota de escopo: | Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules. |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Nota MeSH pública: | 2021 |
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| Nota histórica: | 2021 |
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| Identificador DeCS: | 59323 | ||||||
| ID do descritor: | D000082102 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/2021 | ||||||
| Data de entrada: | 07/07/2020 | ||||||
| Data de revisão: | 27/05/2020 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Immune Checkpoint Proteins
- Conceito preferido
Stimulatory Checkpoint Molecules
- Mais específico
Inhibitory Checkpoint Molecules
- Mais específico
| Identificador do conceito |
M000675777 |
| Nota de escopo | Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules. |
| Termo preferido | Immune Checkpoint Proteins |
| Termo(s) alternativo(s) |
Checkpoint Molecule, Immune Checkpoint Protein, Immune Immune Checkpoint Molecule Immune Checkpoint Molecules Immune Checkpoint Protein Molecule, Immune Checkpoint Protein, Immune Checkpoint |
| Identificador do conceito |
M000675778 |
| Termo preferido | Stimulatory Checkpoint Molecules |
| Termo(s) alternativo(s) |
Checkpoint Molecule, Stimulatory Stimulatory Checkpoint Molecule |
| Identificador do conceito |
M000675779 |
| Termo preferido | Inhibitory Checkpoint Molecules |
| Termo(s) alternativo(s) |
Checkpoint Molecule, Inhibitory Inhibitory Checkpoint Molecule |
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