Visão selecionada em Inglês
| Descritor em português: | Hidroximetilglutaril-CoA Sintase | ||||||
| Descritor em inglês: | Hydroxymethylglutaryl-CoA Synthase | ||||||
| Descritor em espanhol: |
Hidroximetilglutaril-CoA Sintasa
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| Descritor em francês: | Hydroxymethylglutaryl-coA synthase | ||||||
| Termo(s) alternativo(s): |
3 hydroxy 3 methylglutaryl coenzyme A synthase 3-hydroxy-3-methylglutaryl-coenzyme A synthase A synthase, 3-hydroxy-3-methylglutaryl-coenzyme CoA Synthase, HMG HMG CoA Synthase HMG-CoA synthase Hydroxymethylglutaryl CoA Synthase Synthase, HMG CoA Synthase, Hydroxymethylglutaryl-CoA synthase, 3-hydroxy-3-methylglutaryl-coenzyme A synthase, HMG-CoA |
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| Código(s) hierárquico(s): |
D08.811.913.050.612 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D006904 | ||||||
| Nota de escopo: | An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5. |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Número de registro: | EC 2.3.3.10 | ||||||
| Nome CAS Tipo 1: | (S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) | ||||||
| Indexação Anterior: |
Coenzyme A (1973-1974) Glutarates (1973-1974) Ketoacid-Lyases (1973-1974) |
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| Nota MeSH pública: | 1991; HMG-COA SYNTHASE was indexed under HYDROXYMETHYLGLUTARYL-COA SYNTHASE 2005-2008, & under COENZYME A LIGASES 2001-2005 |
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| Nota histórica: | 1991(1975); |
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| Versão alternativa: | HMG COA SYNTHASE |
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| Identificador DeCS: | 7075 | ||||||
| ID do descritor: | D006904 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/1991 | ||||||
| Data de entrada: | 19/11/1974 | ||||||
| Data de revisão: | 29/04/2019 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Hydroxymethylglutaryl-CoA Synthase
- Conceito preferido
| Identificador do conceito |
M0010773 |
| Nota de escopo | An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5. |
| Termo preferido | Hydroxymethylglutaryl-CoA Synthase |
| Termo(s) alternativo(s) |
3 hydroxy 3 methylglutaryl coenzyme A synthase 3-hydroxy-3-methylglutaryl-coenzyme A synthase A synthase, 3-hydroxy-3-methylglutaryl-coenzyme CoA Synthase, HMG HMG CoA Synthase HMG-CoA synthase Hydroxymethylglutaryl CoA Synthase Synthase, HMG CoA Synthase, Hydroxymethylglutaryl-CoA synthase, 3-hydroxy-3-methylglutaryl-coenzyme A synthase, HMG-CoA |
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