Pesquisa
Descritor em português: Proteínas de Neoplasias
Descritor em inglês: Neoplasm Proteins
Descritor em espanhol: Proteínas de Neoplasias
Descritor proteínas de neoplasias
Termo(s) alternativo(s) proteínas de tumores
Nota de escopo: PROTEÍNAS cuya expresión anormal (por exceso o por defecto) se asocia al desarrollo, crecimiento o progresión de las NEOPLASIAS. Algunas proteínas de neoplasias son ANTÍGENOS DE NEOPLASIAS, es decir, inducen una reacción inmune al tumor. Se han caracterizado muchas proteínas de neoplasias, que se utilizan como MARCADORES TUMORALES BIOLÓGICOS, cuando son detectables en células y líquidos corporales, para vigilar la existencia o crecimiento de tumores. La expresión anormal de las PROTEINAS ONCOGÉNICAS está implicada en la transformación neoplásica, mientras que la pérdida de la expresión de las PROTEINAS SUPRESORAS DE TUMOR está relacionada con la pérdida del control del crecimiento y progresión de la neoplasia.
Descritor em francês: Protéines tumorales
Termo(s) alternativo(s): Proteins, Neoplasm
Código(s) hierárquico(s): D12.776.624
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D009363
Nota de escopo: Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Nota de indexação: IM & coord with specific protein (IM) + specific histol type (IM) + specific organ/neoplasms term (IM); Manual 24.4.4.4
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Versão alternativa: NEOPL PROTEINS
Veja também os descritores: Antigens, Neoplasm MeSH
Biomarkers, Tumor MeSH
Identificador DeCS: 9556
ID do descritor: D009363
Classificação da NLM: QZ 210
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1963
Data de entrada: 01/01/1999
Data de revisão: 13/07/2015
Neoplasm Proteins - Conceito preferido
Identificador do conceito M0014578
Nota de escopo Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Termo preferido Neoplasm Proteins
Termo(s) alternativo(s) Proteins, Neoplasm



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