Descriptor English: | Pactamycin | ||||
Descriptor Spanish: |
Pactamicina
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Descriptor Portuguese: | Pactamicina | ||||
Descriptor French: | Pactamycine | ||||
Tree number(s): |
D02.241.223.100.300.450 D02.241.511.390.450 D02.455.426.559.389.127.281.450 D02.455.426.559.389.657.410.450 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D010142 | ||||
Scope note: | Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Antibiotics, Antineoplastic Antibióticos Antineoplásicos Antibióticos Antineoplásicos Antibiotiques antinéoplasiques antibióticos antineoplásicos Protein Synthesis Inhibitors Inhibidores de la Síntesis de la Proteína Inibidores da Síntese de Proteínas Inhibiteurs de la synthèse protéique inhibidores de la síntesis proteica |
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Registry Number: | 23668-11-3 | ||||
CAS Type 1 Name: | Benzoic acid, 2-hydroxy-6-methyl-, (5-((3-acetylphenyl)amino)-4-amino-3-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester, (1S-(1alpha,2beta,3alpha,3(R*),4alpha,5beta))- | ||||
Previous Indexing: |
Antibiotics, Antineoplastic (1972-1974) |
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Public MeSH Note: | 91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90 |
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History Note: | 91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90 |
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DeCS ID: | 10329 | ||||
Unique ID: | D010142 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1991/01/01 | ||||
Date of Entry: | 1974/11/19 | ||||
Revision Date: | 2012/07/03 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals
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Pactamycin
- Preferred
Concept UI |
M0015738 |
Scope note | Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis. |
Preferred term | Pactamycin |
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