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Descriptor English: Pactamycin
Descriptor Spanish: Pactamicina
Descriptor pactamicina
Scope note: Antibiótico producido por Streptomyces pactum utilizado como agente antineoplásico. Se utiliza también como herramienta en bioquímica porque inhibe algunos pasos de la síntesis proteica.
Descriptor Portuguese: Pactamicina
Descriptor French: Pactamycine
Tree number(s): D02.241.223.100.300.450
D02.241.511.390.450
D02.455.426.559.389.127.281.450
D02.455.426.559.389.657.410.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010142
Scope note: Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Antibióticos Antineoplásicos
Antibióticos Antineoplásicos
Antibiotiques antinéoplasiques
antibióticos antineoplásicos
Protein Synthesis Inhibitors
Inhibidores de la Síntesis de la Proteína
Inibidores da Síntese de Proteínas
Inhibiteurs de la synthèse protéique
inhibidores de la síntesis proteica
Registry Number: 23668-11-3
CAS Type 1 Name: Benzoic acid, 2-hydroxy-6-methyl-, (5-((3-acetylphenyl)amino)-4-amino-3-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester, (1S-(1alpha,2beta,3alpha,3(R*),4alpha,5beta))-
Previous Indexing: Antibiotics, Antineoplastic (1972-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
History Note: 91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
DeCS ID: 10329
Unique ID: D010142
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2012/07/03
Pactamycin - Preferred
Concept UI M0015738
Scope note Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
Preferred term Pactamycin



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