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Descriptor English: Pactamycin
Descriptor Spanish: Pactamicina
Descriptor pactamicina
Scope note: Antibiótico producido por Streptomyces pactum utilizado como agente antineoplásico. Se utiliza también como herramienta en bioquímica porque inhibe algunos pasos de la síntesis proteica.
Descriptor Portuguese: Pactamicina
Descriptor French: Pactamycine
Tree number(s): D02.241.223.100.300.450
D02.241.511.390.450
D02.455.426.559.389.127.281.450
D02.455.426.559.389.657.410.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010142
Scope note: Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Protein Synthesis Inhibitors
Registry Number: 23668-11-3
CAS Type 1 Name: Benzoic acid, 2-hydroxy-6-methyl-, (5-((3-acetylphenyl)amino)-4-amino-3-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester, (1S-(1alpha,2beta,3alpha,3(R*),4alpha,5beta))-
Previous Indexing: Antibiotics, Antineoplastic (1972-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
History Note: 91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
DeCS ID: 10329
Unique ID: D010142
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2012/07/03
Pactamycin - Preferred
Concept UI M0015738
Scope note Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
Preferred term Pactamycin



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