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Descriptor English: Pentylenetetrazole
Descriptor Spanish: Pentilenotetrazol
Descriptor Portuguese: Pentilenotetrazol
Descriptor French: Pentétrazol
Entry term(s): Cardiazol
Corasol
Corazol
Corazole
Korazol
Korazole
Leptazole
Metrazol
Metrazole
Pentamethylenetetrazole
Pentazol
Pentetrazole
Pentylenetetrazol
Tree number(s): D03.383.066.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010433
Scope note: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Convulsants
GABA Antagonists
Registry Number: WM5Z385K7T
CAS Type 1 Name: 5H-Tetrazolo(1,5-a)azepine, 6,7,8,9-tetrahydro-
DeCS ID: 10627
Unique ID: D010433
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Pentylenetetrazole - Preferred
Concept UI M0016203
Scope note A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
Preferred term Pentylenetetrazole
Entry term(s) Leptazole
Pentamethylenetetrazole
Pentetrazole
Pentylenetetrazol
Cardiazol - Narrower
Concept UI M0373142
Preferred term Cardiazol
Corasol - Narrower
Concept UI M0373141
Preferred term Corasol
Entry term(s) Corazol
Corazole
Korazol
Korazole
Pentazol - Narrower
Concept UI M0373139
Preferred term Pentazol
Metrazol - Narrower
Concept UI M0373140
Preferred term Metrazol
Entry term(s) Metrazole



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