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Descriptor English: Picibanil
Descriptor Spanish: Picibanil
Descriptor picibanil
Scope note: Preparados liofilizados de cepas de baja virulencia (cepa Su) de Streptococcus pyogenes (S. hemolyticus), que se inactivan al calentarlos con penicilina G. Se ha propuesto su uso como antineoplásico no citotóxico, debido a su actividad estimulante del sistema inmunitario.
Descriptor Portuguese: Picibanil
Descriptor French: Picibanil
Entry term(s): NSC B116209
NSC-B116209
NSCB116209
OK 432
OK-432
OK432
Picibanyl
Streptococcal OK 432
Streptococcal OK-432
Streptococcal OK432
Streptococcal Preparation OK 432
Streptococcal Preparation OK-432
Streptococcal Preparation OK432
Tree number(s): D20.215.659
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010844
Scope note: A lyophilized preparation of a low-virulence strain (SU) of Streptococcus pyogenes (S. hemolyticus), inactivated by heating with penicillin G. It has been proposed as a noncytotoxic antineoplastic agent because of its immune system-stimulating activity.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Registry Number: 39325-01-4
CAS Type 1 Name: Picibanil
Previous Indexing: Streptococcus (1966-1977)
Public MeSH Note: 91; was see under BIOLOGICAL PRODUCTS 1983-90; was STREPTOCOCCAL PREPARATION OK-432 see under BIOLOGICAL PRODUCTS 1978-82
Online Note: use PICIBANIL to search STREPTOCOCCAL PREPARATION OK-432 1978-82
History Note: 91(83); was see under BIOLOGICAL PRODUCTS 1983-90; was STREPTOCOCCAL PREPARATION OK-432 see under BIOLOGICAL PRODUCTS 1978-82
Related: Streptococcus pyogenes MeSH
DeCS ID: 11276
Unique ID: D010844
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/22
Revision Date: 2005/06/30
Picibanil - Preferred
Concept UI M0016834
Scope note A lyophilized preparation of a low-virulence strain (SU) of Streptococcus pyogenes (S. hemolyticus), inactivated by heating with penicillin G. It has been proposed as a noncytotoxic antineoplastic agent because of its immune system-stimulating activity.
Preferred term Picibanil
Entry term(s) Picibanyl
NSC-B116209 - Narrower
Concept UI M0373874
Preferred term NSC-B116209
Entry term(s) NSC B116209
NSCB116209
OK-432 - Narrower
Concept UI M0373873
Preferred term OK-432
Entry term(s) OK 432
OK432
Streptococcal OK 432
Streptococcal OK-432
Streptococcal OK432
Streptococcal Preparation OK 432
Streptococcal Preparation OK-432
Streptococcal Preparation OK432



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