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Descriptor English: Ribonucleoside Diphosphate Reductase
Descriptor Spanish: Ribonucleósido Difosfato Reductasa
Descriptor ribonucleósido difosfato reductasa
Scope note: Enzima de la clase oxirreductasa que cataliza la formación de 2'-desoxirribonucleótidos a partir de los correspondiente ribonucléotidos usando NADPH como donante de electrones último. Los desoxirribunucleósido disfosfatos se utilizan en la síntesis de ADN. (Dorland, 27th ed) EC 1.17.4.1.
Descriptor Portuguese: Ribonucleosídeo Difosfato Redutase
Descriptor French: Ribonucleoside diphosphate reductase
Entry term(s): Diphosphate Reductase, Ribonucleoside
Reductase, Ribonucleoside Diphosphate
Reductase, UDP
UDP Reductase
Tree number(s): D08.811.682.810.567
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012262
Scope note: An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. (From Dorland, 27th ed) EC 1.17.4.1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.17.4.1
CAS Type 1 Name: 2'-Deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase
Public MeSH Note: 91; was see under RIBONUCLEOTIDE REDUCTASES 1975-90
Online Note: search RIBONUCLEOTIDE REDUCTASES 1974
History Note: 91(75); was see under RIBONUCLEOTIDE REDUCTASES 1975-90
DeCS ID: 12671
Unique ID: D012262
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Ribonucleoside Diphosphate Reductase - Preferred
Concept UI M0019072
Scope note An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. (From Dorland, 27th ed) EC 1.17.4.1.
Preferred term Ribonucleoside Diphosphate Reductase
Entry term(s) Diphosphate Reductase, Ribonucleoside
Reductase, Ribonucleoside Diphosphate
UDP Reductase - Narrower
Concept UI M0019073
Preferred term UDP Reductase
Entry term(s) Reductase, UDP



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