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Descriptor English: Rutamycin
Descriptor Spanish: Rutamicina
Descriptor rutamicina
Entry term(s) oligomicina D
Scope note: Antibiótico macrólido del grupo de la oligomicina, obtenido de Streptomyces rutgersensis. Se utiliza en citoquímica como herramienta para inhibir varias ATPasas y desacoplar la fosforilación oxidativa del transporte electrónico y también clínicamente como agente antifúngico.
Descriptor Portuguese: Rutamicina
Descriptor French: Rutamycine
Entry term(s): A 272
A-272
A272
Oligomycin D
RR 32705
RR-32705
RR32705
Tree number(s): D02.540.505.620.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012427
Scope note: A macrolide antibiotic of the oligomycin group, obtained from Streptomyces rutgersensis. It is used in cytochemistry as a tool to inhibit various ATPases and to uncouple oxidative phosphorylation from electron transport and also clinically as an antifungal agent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Antifungal Agents
Enzyme Inhibitors
Uncoupling Agents
Registry Number: 4736R46V0G
CAS Type 1 Name: Oligomycin A, 26-demethyl-
Previous Indexing: Antibiotics, Antifungal (1969-1974)
Public MeSH Note: 91; was see under OLIGOMYCINS 1982-90; was see under ANTIBIOTICS, ANTIFUNGAL 1975-81
History Note: 91(75); was see under OLIGOMYCINS 1982-90; was see under ANTIBIOTICS, ANTIFUNGAL 1975-81
DeCS ID: 12800
Unique ID: D012427
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/08
Rutamycin - Preferred
Concept UI M0019312
Scope note A macrolide antibiotic of the oligomycin group, obtained from Streptomyces rutgersensis. It is used in cytochemistry as a tool to inhibit various ATPases and to uncouple oxidative phosphorylation from electron transport and also clinically as an antifungal agent.
Preferred term Rutamycin
Entry term(s) Oligomycin D
RR-32705 - Narrower
Concept UI M0352041
Preferred term RR-32705
Entry term(s) RR 32705
RR32705
A-272 - Narrower
Concept UI M0352042
Preferred term A-272
Entry term(s) A 272
A272



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