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Descriptor English: Sarin
Descriptor Spanish: Sarín
Descriptor sarín
Scope note: Compuesto éster organofosforado que produce una potente e irreversible inhibición de la colinesterasa. Es tóxico para el sistema nervioso y un agente de guerra química.
Descriptor Portuguese: Sarina
Descriptor French: Sarin
Entry term(s): Gas, Sarin
Phosphonofluoridate, o-Isopropylmethyl
Phosphonofluoridate, ortho-Isopropylmethyl
Sarin Gas
o Isopropylmethyl Phosphonofluoridate
o-Isopropylmethyl Phosphonofluoridate
ortho Isopropylmethyl Phosphonofluoridate
ortho-Isopropylmethyl Phosphonofluoridate
Tree number(s): D02.705.429.750.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012524
Scope note: An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Chemical Warfare Agents
Cholinesterase Inhibitors
Registry Number: B4XG72QGFM
CAS Type 1 Name: Phosphonofluoridic acid, methyl-, 1-methylethyl ester
Previous Indexing: Cholinesterase Inhibitors (1966-1971)
Organophosphorus Compounds (1971)
Public MeSH Note: 91; was see under ORGANOPHOSPHORUS COMPOUNDS 1972-90
History Note: 91(72); was see under ORGANOPHOSPHORUS COMPOUNDS 1972-90
DeCS ID: 12905
Unique ID: D012524
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2014/12/02
Sarin - Preferred
Concept UI M0019449
Scope note An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.
Preferred term Sarin
Entry term(s) Phosphonofluoridate, o-Isopropylmethyl
Phosphonofluoridate, ortho-Isopropylmethyl
o Isopropylmethyl Phosphonofluoridate
o-Isopropylmethyl Phosphonofluoridate
ortho Isopropylmethyl Phosphonofluoridate
ortho-Isopropylmethyl Phosphonofluoridate
Sarin Gas - Narrower
Concept UI M000599527
Preferred term Sarin Gas
Entry term(s) Gas, Sarin



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