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Descriptor English: Semustine
Descriptor Spanish: Semustina
Descriptor semustina
Entry term(s) metil-CCNU
Scope note: Derivado 4-metilo de la LOMUSTINA (CCNU). Agente antineoplásico que funciona como agente alquilante.
Descriptor Portuguese: Semustina
Descriptor French: Sémustine
Entry term(s): Me CCNU
Me-CCNU
MeCCNU
Methyl CCNU
Methyl-CCNU
NSC 95441
NSC-95441
NSC95441
Tree number(s): D02.065.950.594.440.700
D02.654.692.440.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012673
Scope note: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Alkylating
Registry Number: 13909-09-6
CAS Type 1 Name: Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-
Previous Indexing: Cyclohexanes (1966-1974)
Nitroso Compounds (1966-1972)
Nitrosourea Compounds (1973-1974)
Urea (1966-1972)
Public MeSH Note: 91; was see under NITROSOUREA COMPOUNDS 1975-90
History Note: 91(75); was see under NITROSOUREA COMPOUNDS 1975-90
DeCS ID: 13056
Unique ID: D012673
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2001/07/25
Semustine - Preferred
Concept UI M0019643
Scope note 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
Preferred term Semustine
Entry term(s) Me CCNU
Me-CCNU
MeCCNU
Methyl CCNU
Methyl-CCNU
NSC-95441 - Narrower
Concept UI M0352090
Preferred term NSC-95441
Entry term(s) NSC 95441
NSC95441



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