DeCS

Descriptor English:

Azathioprine

Descriptor Spanish:

Azatioprina

Spanish from Spain

Descriptor	azatioprina
Scope note:	Agente inmunosupresor que se utiliza, en combinación con ciclofosfamida e hidrocloroquina, en el tratamiento de la artritis reumatoide. De acuerdo con el Cuarto Informe Anual sobre Carcinógenos (NTP 85-002, 1985), esta sustancia ha sido considerada como cancerígena. (Merck Index, 11th ed)

Descriptor Portuguese:

Azatioprina

Descriptor French:

Azathioprine

Entry term(s):

Azathioprine de sodium
Azathioprine sodique
Imuran
Imurel
Sulfate d'azathioprine

Tree number(s):

D02.886.759.111
D03.633.100.759.570.090
D13.570.900.111

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D001379

Scope note:

An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antimetabolites
Antimetabolites, Antineoplastic
Immunosuppressive Agents
Antirheumatic Agents

Registry Number:

MRK240IY2L

CAS Type 1 Name:

1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-

DeCS ID:

1394

Unique ID:

D001379

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents