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Descriptor English: Thioinosine
Descriptor Spanish: Tioinosina
Descriptor tioinosina
Entry term(s) 6-mercaptopurina ribósido
Scope note: Análogo sulfhidrilo de la INOSINA que inhibe el transporte de nucleósidos a través de las membranas plasmáticas de los eritrocitos, y que tiene propiedades inmunosupresoras. Se ha utilizado de forma similar a la MERCAPTOPURINA en el tratamiento de la leucemia.
Descriptor Portuguese: Tioinosina
Descriptor French: Thioinosine
Entry term(s): 6 Mercaptopurine Riboside
6-Mercaptopurine Riboside
NSC-4911
Riboside, 6-Mercaptopurine
Ribosyl 6 mercaptopurine
Ribosyl-6-mercaptopurine
Tree number(s): D02.886.759.800
D03.633.100.759.590.616.900
D13.570.583.616.900
D13.570.800.573.900
D13.570.900.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013868
Scope note: Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in the treatment of leukemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p503)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Immunosuppressive Agents
Registry Number: 46S541971T
CAS Type 1 Name: Inosine, 6-thio-
Previous Indexing: Inosine (1973-1974)
Mercaptopurine (1973-1974)
Public MeSH Note: 91; was see under INOSINE 1975-90
History Note: 91(75); was see under INOSINE 1975-90
DeCS ID: 14250
Unique ID: D013868
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/06/01
Thioinosine - Preferred
Concept UI M0021358
Scope note Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in the treatment of leukemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p503)
Preferred term Thioinosine
Entry term(s) 6 Mercaptopurine Riboside
6-Mercaptopurine Riboside
Riboside, 6-Mercaptopurine
Ribosyl 6 mercaptopurine
Ribosyl-6-mercaptopurine
NSC-4911 - Narrower
Concept UI M0373893
Preferred term NSC-4911



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