Descriptor English: | Mercaptopurine | ||||||
Descriptor Spanish: |
Mercaptopurina
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Descriptor Portuguese: | Mercaptopurina | ||||||
Descriptor French: | Mercaptopurine | ||||||
Entry term(s): |
1,7-Dihydro-6H-purine-6-thione 6 Mercaptopurine 6 Mercaptopurine Monohydrate 6 Thiohypoxanthine 6 Thiopurine 6-Mercaptopurine 6-Mercaptopurine Monohydrate 6-Thiohypoxanthine 6-Thiopurine 6H-Purine-6-thione, 1,7-dihydro- BW 57 323H BW 57-323H BW 57323H Leupurin Mecaptopurine Anhydrous Mercaptopurina Wellcome Puri-Nethol Purimethol Purinethol |
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Tree number(s): |
D02.886.489.534 D03.633.100.759.570 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015122 | ||||||
Scope note: | An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Antimetabolites Antimetabolites, Antineoplastic Immunosuppressive Agents Nucleic Acid Synthesis Inhibitors |
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Registry Number: | E7WED276I5 | ||||||
Public MeSH Note: | 2018; see 6-Mecaptopurine 1985-2017; see MERCAPTOPURINE 1963-1984; see ARABINOSYL-6-MERCAPTOPURINE 1975-1991; MERCAPTOPURINE was indexed under 6-MERCAPTOPURINE 1975-1990 |
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History Note: | 2018(1985) |
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DeCS ID: | 8800 | ||||||
Unique ID: | D015122 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1985/01/01 | ||||||
Date of Entry: | 1999/01/01 | ||||||
Revision Date: | 2018/07/05 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
|
Mercaptopurine
- Preferred
Purinethol
- Narrower
Mercaptopurina Wellcome
- Narrower
Leupurin
- Narrower
BW 57-323H
- Narrower
Purimethol
- Narrower
Mecaptopurine Anhydrous
- Related but not broader or narrower
Concept UI |
M0023263 |
Scope note | An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia. |
Preferred term | Mercaptopurine |
Entry term(s) |
1,7-Dihydro-6H-purine-6-thione 6 Mercaptopurine 6 Mercaptopurine Monohydrate 6 Thiohypoxanthine 6 Thiopurine 6-Mercaptopurine 6-Mercaptopurine Monohydrate 6-Thiohypoxanthine 6-Thiopurine 6H-Purine-6-thione, 1,7-dihydro- |
Concept UI |
M0352351 |
Preferred term | Purinethol |
Entry term(s) |
Puri-Nethol |
Concept UI |
M0474764 |
Preferred term | Mercaptopurina Wellcome |
Concept UI |
M0352353 |
Preferred term | Leupurin |
Concept UI |
M0352354 |
Preferred term | BW 57-323H |
Entry term(s) |
BW 57 323H BW 57323H |
Concept UI |
M0352352 |
Preferred term | Purimethol |
Concept UI |
M000618306 |
Preferred term | Mecaptopurine Anhydrous |
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