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Descriptor English: Thromboxane A2
Descriptor Spanish: Tromboxano A2
Descriptor tromboxano A2
Entry term(s) sustancia de contracción de la aorta del conejo
Scope note: Compuesto intermedio inestable entre los endoperóxidos de prostaglandina y el tromboxano B2. El compuesto tiene una estructura oxaneoxeano bicíclica. Es un potente inductor de la agtregación plaquetaria y produce vasoconstricción. Es el componente principal de la sustancia de contracción de la aorta del conejo (SCC).
Descriptor Portuguese: Tromboxano A2
Descriptor French: Thromboxane A2
Entry term(s): A2, Thromboxane
Rabbit Aorta Contracting Substance
Tree number(s): D10.251.355.255.100.825.800
D10.251.355.310.166.971.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013928
Scope note: An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
Annotation: /biosyn /physiol permitted
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 57576-52-0
CAS Type 1 Name: Thromboxa-5,13-dien-1-oic acid, 9,11-epoxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-
Previous Indexing: Fatty Acids, Unsaturated (1973-1974)
Hydroxy Acids (1975-1977)
Pyrans (1966-1977)
Public MeSH Note: 86; was see under THROMBOXANES 1978-85
History Note: 86(78); was see under THROMBOXANES 1978-85
DeCS ID: 14314
Unique ID: D013928
NLM Classification: QU 90
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1977/05/23
Revision Date: 2015/06/23
Thromboxane A2 - Preferred
Concept UI M0021438
Scope note An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
Preferred term Thromboxane A2
Entry term(s) A2, Thromboxane
Rabbit Aorta Contracting Substance - Broader
Concept UI M0021437
Preferred term Rabbit Aorta Contracting Substance



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