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Descriptor English: Tilorone
Descriptor Spanish: Tilorona
Descriptor Portuguese: Tilorona
Descriptor French: Tilorone
Entry term(s): Amiksin
Amixin
Amyxin
Bis DEAE Fluorenone
Bis-DEAE-Fluorenone
Hydrochloride, Tilorone
Tilorone Hydrochloride
Tree number(s): D02.455.426.559.847.389.850
D04.615.389.850
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013994
Scope note: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Inflammatory Agents
Antineoplastic Agents
Antiviral Agents
Interferon Inducers
Registry Number: O6W7VEW6KS
CAS Type 1 Name: 9H-Fluoren-9-one, 2,7-bis(2-(diethylamino)ethoxy)-
Previous Indexing: Diethylamines (1974)
Fluorenes (1971-1974)
Public MeSH Note: 91; was see under FLUORENES 1975-90; AMYXIN was indexed under TILORONE/analogs & derivatives 1988-91
Online Note: use TILORONE (NM) to search AMYXIN (NM) 1988-91
History Note: 91(75); was see under FLUORENES 1975-90; AMYXIN was AMYXIN (NM) 1988-91
DeCS ID: 14381
Unique ID: D013994
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/08
Tilorone - Preferred
Concept UI M0021536
Scope note An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
Preferred term Tilorone
Entry term(s) Bis DEAE Fluorenone
Bis-DEAE-Fluorenone
Tilorone Hydrochloride - Narrower
Concept UI M0329668
Preferred term Tilorone Hydrochloride
Entry term(s) Amiksin
Amixin
Amyxin
Hydrochloride, Tilorone



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