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Descriptor English: Aconitine
Descriptor Spanish: Aconitina
Descriptor aconitina
Entry term(s) (1-alfa,3-alfa,6-alfa,14-alfa,15-alfa,16-beta)-20-etil-1,6,16-trimetoxi-4-(metoximetil)-aconitano-3,8,13,14,15-pentol 8-acetato 14-benzoato
acetilbenzoilaconina
Scope note: Alcaloide norditerpenoide de 19 C (DITERPENOS) obtenido de la raíz de ACONITUM, de DELPHINIUM y de las espuelas de caballero. Activa los CANALES DE SODIO DEPENDIENTES DE VOLTAJE. También se ha utilizado para inducir ARRITMIAS en experimentación en animales y tiene propiedades antiinflamatorias y antineurálgicas.
Descriptor Portuguese: Aconitina
Descriptor French: Aconitine
Entry term(s): Acetylbenzoyl aconine
Acetylbenzoyl-aconine
Acetylbenzoylaconine
Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-
Tree number(s): D02.455.849.291.184.037
D03.132.301.030
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000157
Scope note: A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM; DELPHINIUM and larkspurs. It activates VOLTAGE-GATED SODIUM CHANNELS. It has been used to induce ARRHYTHMIAS in experimental animals and it has anti-inflammatory and anti-neuralgic properties.
Annotation: ACONITE (see ACONITUM) is also available
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Adjuvants, Immunologic
Voltage-Gated Sodium Channel Agonists
Registry Number: X8YN71D5WC
CAS Type 1 Name: Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-
Previous Indexing: Aconite (1972-1974)
Public MeSH Note: 91; was see under ACONITE 1975-90
History Note: 91(75); was see under ACONITE 1975-90
DeCS ID: 164
Unique ID: D000157
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2019/06/18
Aconitine - Preferred
Concept UI M0000236
Scope note A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM; DELPHINIUM and larkspurs. It activates VOLTAGE-GATED SODIUM CHANNELS. It has been used to induce ARRHYTHMIAS in experimental animals and it has anti-inflammatory and anti-neuralgic properties.
Preferred term Aconitine
Entry term(s) Acetylbenzoyl aconine
Acetylbenzoyl-aconine
Acetylbenzoylaconine
Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-



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