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Descriptor English: Bongkrekic Acid
Descriptor Spanish: Ácido Bongcréquico
Descriptor ácido bongkrecico
Entry term(s) flavotoxina A
Scope note: Antibiótico producido por Pseudomonas cocovenenans. Es inhibidor de las TRANSLOCASAS MITOCONDRIALES DE ADP Y ATP. Específicamente bloquea la salida del nucleótido adenina de las mitocondrias al aumentar la unión a la membrana.
Descriptor Portuguese: Ácido Bongcréquico
Descriptor French: Acide bongkrékique
Entry term(s): Bongkrekate
Flavotoxin A
Tree number(s): D02.241.081.337.075
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001865
Scope note: An antibiotic produced by Pseudomonas cocovenenans. It is an inhibitor of MITOCHONDRIAL ADP, ATP TRANSLOCASES. Specifically, it blocks adenine nucleotide efflux from mitochondria by enhancing membrane binding.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Registry Number: 11076-19-0
CAS Type 1 Name: 2,4,8,10,14,18,20-Docosaheptaenedioic acid, 20-(carboxymethyl)-6-methoxy-2,5,17-trimethyl-, (R-(R*,S*-(E,Z,Z,E,E,Z,E)))-
Previous Indexing: Antibiotics (1973-1974)
Carboxylic Acids (1973-1974)
Pseudomonas (1968-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS 1975-90
History Note: 91(75); was see under ANTIBIOTICS 1975-90
DeCS ID: 1889
Unique ID: D001865
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/30
Bongkrekic Acid - Preferred
Concept UI M0002799
Scope note An antibiotic produced by Pseudomonas cocovenenans. It is an inhibitor of MITOCHONDRIAL ADP, ATP TRANSLOCASES. Specifically, it blocks adenine nucleotide efflux from mitochondria by enhancing membrane binding.
Preferred term Bongkrekic Acid
Entry term(s) Flavotoxin A
Bongkrekate - Narrower
Concept UI M0002800
Preferred term Bongkrekate



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