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Descriptor English: Thrombasthenia
Descriptor Spanish: Trombastenia
Descriptor trombastenia
Entry term(s) deficiencia de glucoproteína 2b-3a plaquetaria
deficiencia de glucoproteína IIb-IIIa plaquetaria
deficiencia del complejo GP 2b-3a
deficiencia del complejo GP IIb-IIIa
deficiencia del complejo glucoproteína IIb-IIIa
deficiencia del receptor plaquetario del fibrinógeno
trombastenia de Glanzmann
trombastenia de Glanzmann de tipo A
Scope note: Trastorno congénito hemorrágico que se caracteriza por tiempo de hemorragia prolongado, ausencia de agregación plaquetaria como respuesta a la mayoría de los agentes, especialmente ADP, y retracción del coágulo alterada o ausente. Las membranas plaquetarias son deficientes o tienen un defecto en el complejo de la glicoproteína IIb-IIIa (COMPLEJO PLAQUETARIO DE LA GLICOPROTEÍNA GPIIB-IIIA).
Descriptor Portuguese: Trombastenia
Descriptor French: Thrombasthénie
Entry term(s): Deficiency of GP 2b 3a Complex
GP IIb-IIIa Complex, Deficiency Of
Glanzmann Thrombasthenia
Glanzmann Thrombasthenia, Type A
Glycoprotein Complex IIb-IIIa, Deficiency Of
Platelet Fibrinogen Receptor, Deficiency of
Platelet Glycoprotein 2b-3a Deficiency
Platelet Glycoprotein IIb-IIIa Deficiency
Thrombasthenia of Glanzmann and Naegeli
Thrombasthenia, Glanzmann
Thrombasthenias
Tree number(s): C15.378.100.100.820
C15.378.140.810
C15.378.463.810
C16.320.099.820
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013915
Scope note: A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Blood Platelet Disorders (1967-1985)
Public MeSH Note: 1991; see BLOOD PLATELET DISORDERS 1986-1990
History Note: 1991(1986); use BLOOD PLATELET DISORDERS 1986-1990
Related: Platelet Glycoprotein GPIIb-IIIa Complex MeSH
DeCS ID: 19008
Unique ID: D013915
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1985/03/11
Revision Date: 2012/07/03
Thrombasthenia - Preferred
Concept UI M0021418
Scope note A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).
Preferred term Thrombasthenia
Entry term(s) Deficiency of GP 2b 3a Complex
GP IIb-IIIa Complex, Deficiency Of
Glanzmann Thrombasthenia
Glanzmann Thrombasthenia, Type A
Glycoprotein Complex IIb-IIIa, Deficiency Of
Platelet Fibrinogen Receptor, Deficiency of
Platelet Glycoprotein 2b-3a Deficiency
Platelet Glycoprotein IIb-IIIa Deficiency
Thrombasthenia of Glanzmann and Naegeli
Thrombasthenia, Glanzmann
Thrombasthenias



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