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Descriptor English: Philadelphia Chromosome
Descriptor Spanish: Cromosoma Filadelfia
Descriptor cromosoma Filadelfia
Entry term(s) cromosoma Ph1
cromosoma Philadelphia
Scope note: Forma aberrante del cromosoma 22 caracterizada por la translocación del extremo distal del cromosoma 9 desde 9q34 hasta el brazo largo del cromosoma 22 en 22q11. Se encuentra en las células de la medula ósea del 80-90 por ciento de los pacientes afectos de leucemia mielocítica crónica (LEUCEMIA MIELÓGENA CRÓNICA BCR-ABL POSITIVA).
Descriptor Portuguese: Cromossomo Filadélfia
Descriptor French: Chromosome Philadelphie
Entry term(s): 1 Chromosomes, Ph
Chromosome, Ph 1
Chromosome, Ph1
Chromosome, Philadelphia
Chromosomes, Ph 1
Chromosomes, Ph1
Ph 1 Chromosome
Ph 1 Chromosomes
Ph1 Chromosome
Ph1 Chromosomes
Tree number(s): A11.284.187.520.300.325.345.500
A11.284.187.520.300.505.515.500
C23.550.210.870.680
G05.360.162.520.300.325.345.700
G05.360.162.520.300.505.515.700
G05.365.590.175.870.680
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010677
Scope note: An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).
Allowable Qualifiers: DE drug effects
RE radiation effects
Previous Indexing: Chromosome Abnormalities (1966-1967)
Chromosomes (1966-1967)
Chromosomes, Human, 21-22 (1968-1985)
Leukemia, Myelocytic/FG (1966-1985)
Public MeSH Note: 86; was see CHROMOSOMES, HUMAN, 21-22 1978-85
Online Note: search CHROMOSOMES, HUMAN, 21-22 1978-85
History Note: 86; was see CHROMOSOMES, HUMAN, 21-22 1978-85
Related: Oncogene Proteins, Fusion MeSH
DeCS ID: 19631
Unique ID: D010677
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1985/05/03
Revision Date: 2016/06/28
Philadelphia Chromosome - Preferred
Concept UI M0016591
Scope note An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).
Preferred term Philadelphia Chromosome
Entry term(s) 1 Chromosomes, Ph
Chromosome, Ph 1
Chromosome, Ph1
Chromosome, Philadelphia
Chromosomes, Ph 1
Chromosomes, Ph1
Ph 1 Chromosome
Ph 1 Chromosomes
Ph1 Chromosome
Ph1 Chromosomes



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