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Descriptor English: Bretylium Tosylate
Descriptor Spanish: Tosilato de Bretilio
Descriptor tosilato de bretilio
Scope note: Agente que bloquea la secreción de transmisores adrenérgicos y puede tener otras acciones. Inicialmente se utilizó como agente antihipertensor pero actualmente se propone como antiarrítmico.
Descriptor Portuguese: Tosilato de Bretílio
Descriptor French: Tosilate de brétylium
Entry term(s): Bretylate
Bretylium Tosilate
Bretylol
Ornid
Tree number(s): D02.092.877.096.333.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001950
Scope note: An agent that blocks the release of adrenergic transmitters and may have other actions. It was formerly used as an antihypertensive agent, but is now proposed as an anti-arrhythmic.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Arrhythmia Agents
Antihypertensive Agents
Adrenergic Antagonists
Registry Number: 78ZP3YR353
CAS Type 1 Name: Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1)
Previous Indexing: Aryl Sulfonates (1974-1975)
Bretylium Compounds (1969-1975)
Public MeSH Note: 91; was see under BRETYLIUM COMPOUNDS 1976-90
History Note: 91(76); was see under BRETYLIUM COMPOUNDS 1976-90
DeCS ID: 1976
Unique ID: D001950
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2016/07/01
Bretylium Tosylate - Preferred
Concept UI M0002920
Scope note An agent that blocks the release of adrenergic transmitters and may have other actions. It was formerly used as an antihypertensive agent, but is now proposed as an anti-arrhythmic.
Preferred term Bretylium Tosylate
Entry term(s) Bretylium Tosilate
Bretylol - Narrower
Concept UI M0350984
Preferred term Bretylol
Ornid - Narrower
Concept UI M0350983
Preferred term Ornid
Bretylate - Narrower
Concept UI M0463074
Preferred term Bretylate



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