DeCS

Descriptor English:

Bromouracil

Descriptor Spanish:

Bromouracilo

Spanish from Spain

Descriptor	bromouracilo
Scope note:	5-bromo-2,4(1H,3H)-pirimidindiona. Derivado bromado de uracilo que actúa como antimetabolito, sustituyendo la timina en el ADN. Se utiliza, primordialmente, como mutágeno experimental, aunque su desoxirribosa (BROMODESOXIURIDINA) se utiliza para tratamiento de neoplasias.

Descriptor Portuguese:

Bromouracila

Descriptor French:

Bromouracil

Entry term(s):

5-Bromo-uracile
5-Bromouracile
Bromouracile

Tree number(s):

D03.383.742.698.875.237

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D001976

Scope note:

5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.

Annotation:

an antimetabolite

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antimetabolites
Mutagens

Registry Number:

4HK400G5UO

CAS Type 1 Name:

2,4(1H,3H)-Pyrimidinedione, 5-bromo-

DeCS ID:

2006

Unique ID:

D001976

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents