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Descriptor English: Paraproteins
Descriptor Spanish: Paraproteínas
Descriptor paraproteínas
Entry term(s) paraproteína
Scope note: Inmunoglobulinas anormales sintetizadas por células atípicas del SISTEMA MONONUCLEAR FAGOCÍTICO. Las paraproteínas que contienen sólo cadenas ligeras dan lugar a la paraproteinemia de Bence Jones, mientras que la presencia de cadenas pesadas atípicas lleva a la enfermedad de las cadenas pesadas. En la electroforesis, la mayoría de las paraproteínas aparecen como componentes M (gammapatía monoclonal). Las paraproteínas diclonales y policlonales se encuentran con mucha menor frecuencia.
Descriptor Portuguese: Paraproteínas
Descriptor French: Paraprotéines
Tree number(s): D12.776.124.486.485.900
D12.776.124.790.651.900
D12.776.377.715.548.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010266
Scope note: Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
DeCS ID: 22253
Unique ID: D010266
NLM Classification: QW 601
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1976/01/01
Date of Entry: 1975/07/25
Revision Date: 2020/05/27
Paraprotéines - Preferred
Concept UI M0015906
Preferred term Paraprotéines



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