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Descriptor English: Immunoglobulin Variable Region
Descriptor Spanish: Región Variable de Inmunoglobulina
Descriptor Portuguese: Região Variável de Imunoglobulina
Descriptor French: Région variable d'immunoglobuline
Entry term(s): Antibody Fragment, Fv
Antibody Fragments, Fv
Fragment, Fv
Fragment, Fv Antibody
Fragment, Immunoglobulin Fv
Fragments, Fv
Fragments, Fv Antibody
Fragments, Immunoglobulin Fv
Framework Region, Ig
Framework Region, Immunoglobulin
Framework Regions, Ig
Framework Regions, Immunoglobulin
Fv Antibody Fragment
Fv Antibody Fragments
Fv Fragment
Fv Fragment, Immunoglobulin
Fv Fragments
Fv Fragments, Immunoglobulin
Ig Framework Region
Ig Framework Regions
Ig Variable Region
Ig Variable Regions
Immunoglobulin Framework Region
Immunoglobulin Framework Regions
Immunoglobulin Fv Fragment
Immunoglobulin Fv Fragments
Immunoglobulin V
Immunoglobulin Variable Regions
Regions, Immunoglobulin Variable
Variable Region, Ig
Variable Region, Immunoglobulin
Variable Regions, Ig
Variable Regions, Immunoglobulin
Tree number(s): D12.644.541.500.650.500
D12.776.124.486.485.680.650.500
D12.776.124.486.485.797
D12.776.124.790.651.680.650.500
D12.776.124.790.651.797
D12.776.377.715.548.680.650.500
D12.776.377.715.548.797
G02.111.570.060.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007135
Scope note: That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Previous Indexing: Antigenic Determinants (1972-1976)
Binding Sites, Antibody (1973-1976)
Immunoglobulin Fragments (1973-1976)
Immunoglobulins, Fab (1973-1976)
Public MeSH Note: 84; was see under BINDING SITES, ANTIBODY 1977-83
History Note: 84(77); was see under BINDING SITES, ANTIBODY 1977-83
Related: Binding Sites, Antibody MeSH
Immunoglobulin Domains MeSH
DeCS ID: 22209
Unique ID: D007135
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1976/04/16
Revision Date: 2015/11/20
Immunoglobulin Variable Region - Preferred
Concept UI M0011118
Scope note That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
Preferred term Immunoglobulin Variable Region
Entry term(s) Ig Variable Region
Ig Variable Regions
Immunoglobulin V
Immunoglobulin Variable Regions
Regions, Immunoglobulin Variable
Variable Region, Ig
Variable Region, Immunoglobulin
Variable Regions, Ig
Variable Regions, Immunoglobulin
Immunoglobulin Fv Fragments - Related but not broader or narrower
Concept UI M0560635
Scope note The paired immunoglobulin fragments composed of the variable domains of the heavy and light chains.
Preferred term Immunoglobulin Fv Fragments
Entry term(s) Antibody Fragment, Fv
Antibody Fragments, Fv
Fragment, Fv
Fragment, Fv Antibody
Fragment, Immunoglobulin Fv
Fragments, Fv
Fragments, Fv Antibody
Fragments, Immunoglobulin Fv
Fv Antibody Fragment
Fv Antibody Fragments
Fv Fragment
Fv Fragment, Immunoglobulin
Fv Fragments
Fv Fragments, Immunoglobulin
Immunoglobulin Fv Fragment
Framework Region, Immunoglobulin - Narrower
Concept UI M0011116
Preferred term Framework Region, Immunoglobulin
Entry term(s) Framework Region, Ig
Framework Regions, Ig
Framework Regions, Immunoglobulin
Ig Framework Region
Ig Framework Regions
Immunoglobulin Framework Region
Immunoglobulin Framework Regions



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