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Descriptor English: Complement Fixation Tests
Descriptor Spanish: Pruebas de Fijación del Complemento
Descriptor pruebas de fijación del complemento
Entry term(s) prueba de absorción del complemento conglutinado
reacción de conglutinación
tests de fijación del complemento
Scope note: Pruebas serológicas que se basan en la inactivación del complemento por el complejo antígeno-anticuerpo (etapa 1). La unión del complemento libre puede confirmarse por la adición de un segundo sistema antígeno-anticuerpo como el de hematíes y un anticuerpo apropiado a los hematíes (hemolisina) que requiere del complemento para su realización (etapa 2). La ausencia de lisis de los hematíes indica que en la etapa 1 se ha producido una reacción antígeno-anticuerpo específica. Si hay lisis es porque hay complemento libre lo que indica que no ha ocurrido la reacción antígeno-anticuerpo en la etapa 1.
Descriptor Portuguese: Testes de Fixação de Complemento
Descriptor French: Tests de fixation du complément
Entry term(s): Complement Absorption Test, Conglutinating
Complement Fixation Test
Conglutinating Complement Absorption Test
Conglutination Reaction
Conglutination Reactions
Fixation Test, Complement
Fixation Tests, Complement
Reaction, Conglutination
Reactions, Conglutination
Test, Complement Fixation
Tests, Complement Fixation
Tree number(s): E01.370.225.812.735.150
E05.200.812.735.150
E05.478.594.760.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003168
Scope note: Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.
Allowable Qualifiers: AE adverse effects
CL classification
EC economics
ES ethics
HI history
IS instrumentation
MO mortality
MT methods
NU nursing
PX psychology
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Public MeSH Note: CONGLUTINATION REACTION was heading 1975-96 (see under COMPLEMENT FIXATION TESTS 1975-90); COMPLEMENT ABSORPTION TEST, CONGLUTINATING was see CONGLUTINATION REACTION 1992-96
History Note: CONGLUTINATION REACTION was heading 1975-96 (see under COMPLEMENT FIXATION TESTS 1975-90); COMPLEMENT ABSORPTION TEST, CONGLUTINATING was see CONGLUTINATION REACTION 1992-96
DeCS ID: 22395
Unique ID: D003168
NLM Classification: QY 265
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2011/06/24
Complement Fixation Tests - Preferred
Concept UI M0004919
Scope note Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.
Preferred term Complement Fixation Tests
Entry term(s) Complement Fixation Test
Fixation Test, Complement
Fixation Tests, Complement
Test, Complement Fixation
Tests, Complement Fixation
Conglutinating Complement Absorption Test - Narrower
Concept UI M0004920
Preferred term Conglutinating Complement Absorption Test
Entry term(s) Complement Absorption Test, Conglutinating
Conglutination Reaction
Conglutination Reactions
Reaction, Conglutination
Reactions, Conglutination



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