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Descriptor English: Glucagon
Descriptor Spanish: Glucagón
Descriptor glucagón
Scope note: Péptido pancreático de 29 aminoácidos que se forma a partir del proglucagón y que también es el precursor de los PÉPTIDOS GLUCAGONOIDES. El glucagón es secretado por las CÉLULAS ALFA PANCREÁTICAS y desempeña un papel importante en la regulación de la GLUCEMIA, el metabolismo de las cetonas y otros procesos bioquímicos y fisiológicos. (Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p. 1511).
Descriptor Portuguese: Glucagon
Descriptor French: Glucagon
Entry term(s): Glucagon (1-29)
Glukagon
HG Factor
HG-Factor
Hyperglycemic Glycogenolytic Factor
Hyperglycemic-Glycogenolytic Factor
Proglucagon (33-61)
Tree number(s): D06.472.699.587.730.500
D12.644.548.586.730.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005934
Scope note: A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
Annotation: do not confuse with GLUCAGON-LIKE PEPTIDES secreted by the intestine
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Gastrointestinal Agents
Hormones
Registry Number: 9007-92-5
Related: Receptors, Glucagon MeSH
DeCS ID: 22478
Unique ID: D005934
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/05
Glucagon - Preferred
Concept UI M0009314
Scope note A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
Preferred term Glucagon
Entry term(s) Glucagon (1-29)
Glukagon
HG Factor
HG-Factor
Hyperglycemic Glycogenolytic Factor
Hyperglycemic-Glycogenolytic Factor
Proglucagon (33-61)



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