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Descriptor English: Substantia Nigra
Descriptor Spanish: Sustancia Negra
Descriptor sustancia negra
Scope note: Sustancia de color negro en la porción ventral del mesencéfalo o núcleo de células que contienen la sustancia negra. Estas células producen DOPAMINA, un importante neurotransmisor para la regulación del sistema sensitivomotor y el estado de ánimo. La MELANINA, de color oscuro, es un producto intermedio de la síntesis de dopamina.
Descriptor Portuguese: Substância Negra
Descriptor French: Substantia nigra
Entry term(s): Nigra, Substantia
Nigras, Substantia
Substantia Nigras
Tree number(s): A08.186.211.132.659.413.656
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013378
Scope note: The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.
Allowable Qualifiers: AB abnormalities
AH anatomy & histology
BS blood supply
CH chemistry
CY cytology
DE drug effects
DG diagnostic imaging
EM embryology
EN enzymology
GD growth & development
IM immunology
IN injuries
ME metabolism
MI microbiology
PA pathology
PH physiology
PP physiopathology
PS parasitology
RE radiation effects
SU surgery
TR transplantation
UL ultrastructure
VI virology
DeCS ID: 22685
Unique ID: D013378
NLM Classification: WL 310
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/22
Substantia Nigra - Preferred
Concept UI M0020683
Scope note The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.
Preferred term Substantia Nigra
Entry term(s) Nigra, Substantia
Nigras, Substantia
Substantia Nigras



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