Search
Descriptor English: Captopril
Descriptor Spanish: Captopril
Descriptor captopril
Scope note: Inhibidor potente y específico de la PEPTIDIL-DIPEPTIDASA. Bloquea la conversión de ANGIOTENSINA I a ANGIOTENSINA II, vasoconstrictorn y regulador importante de la presión arterial. El captopril actúa suprimiendo el SISTEMA RENINA-ANGIOTENSINA e inhibe las respuestas de presión a la angiotensina exógena.
Descriptor Portuguese: Captopril
Descriptor French: Captopril
Entry term(s): (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
Capoten
Lopirin
SQ 14,225
SQ 14,534
SQ 14225
SQ 14534
SQ-14,225
SQ-14,534
SQ-14225
SQ-14534
SQ14,225
SQ14,534
SQ14225
SQ14534
Tree number(s): D12.125.072.401.623.270
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002216
Scope note: A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Registry Number: 9G64RSX1XD
CAS Type 1 Name: L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-
Previous Indexing: Kininase II/antagonists & inhibitors (1973-1979)
Peptide Peptidohydrolases (1966-1967) /antagonists & inhibitors (1968-1972)
Proline (1966-1974) /antagonists & inhibitors (1975-1979)
Public MeSH Note: 86; was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
Online Note: use CAPTOPRIL to search SQ 14225 1980-93
History Note: 86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
DeCS ID: 23180
Unique ID: D002216
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1979/05/23
Revision Date: 2013/07/08
Captopril - Preferred
Concept UI M0003319
Scope note A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
Preferred term Captopril
Entry term(s) (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
Lopirin - Narrower
Concept UI M0338109
Preferred term Lopirin
SQ-14,534 - Related but not broader or narrower
Concept UI M0003320
Preferred term SQ-14,534
Entry term(s) SQ 14,534
SQ 14534
SQ-14534
SQ14,534
SQ14534
Capoten - Narrower
Concept UI M0003322
Preferred term Capoten
SQ-14,225 - Narrower
Concept UI M0338110
Preferred term SQ-14,225
Entry term(s) SQ 14,225
SQ 14225
SQ-14225
SQ14,225
SQ14225



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey