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Descriptor English: Captopril
Descriptor Spanish: Captopril
Descriptor captopril
Scope note: Inhibidor potente y específico de la PEPTIDIL-DIPEPTIDASA. Bloquea la conversión de ANGIOTENSINA I a ANGIOTENSINA II, vasoconstrictorn y regulador importante de la presión arterial. El captopril actúa suprimiendo el SISTEMA RENINA-ANGIOTENSINA e inhibe las respuestas de presión a la angiotensina exógena.
Descriptor Portuguese: Captopril
Descriptor French: Captopril
Entry term(s): (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
Capoten
Lopirin
SQ 14,225
SQ 14,534
SQ 14225
SQ 14534
SQ-14,225
SQ-14,534
SQ-14225
SQ-14534
SQ14,225
SQ14,534
SQ14225
SQ14534
Tree number(s): D12.125.072.401.623.270
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002216
Scope note: A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Angiotensin-Converting Enzyme Inhibitors
Inhibidores de la Enzima Convertidora de Angiotensina
Inibidores da Enzima Conversora de Angiotensina
Inhibiteurs de l'enzyme de conversion de l'angiotensine
inhibidores de la enzima convertidora de angiotensina
Antihypertensive Agents
Antihipertensivos
Anti-Hipertensivos
Antihypertenseurs
antihipertensivos
Registry Number: 9G64RSX1XD
CAS Type 1 Name: L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-
Previous Indexing: Kininase II/antagonists & inhibitors (1973-1979)
Peptide Peptidohydrolases (1966-1967) /antagonists & inhibitors (1968-1972)
Proline (1966-1974) /antagonists & inhibitors (1975-1979)
Public MeSH Note: 86; was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
Online Note: use CAPTOPRIL to search SQ 14225 1980-93
History Note: 86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
DeCS ID: 23180
Unique ID: D002216
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1979/05/23
Revision Date: 2013/07/08
Captopril - Preferred
Concept UI M0003319
Scope note A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
Preferred term Captopril
Entry term(s) (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
Lopirin - Narrower
Concept UI M0338109
Preferred term Lopirin
SQ-14,534 - Related but not broader or narrower
Concept UI M0003320
Preferred term SQ-14,534
Entry term(s) SQ 14,534
SQ 14534
SQ-14534
SQ14,534
SQ14534
Capoten - Narrower
Concept UI M0003322
Preferred term Capoten
SQ-14,225 - Narrower
Concept UI M0338110
Preferred term SQ-14,225
Entry term(s) SQ 14,225
SQ 14225
SQ-14225
SQ14,225
SQ14225



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