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Descriptor in English: Chromomycins
Descriptor in Spanish: Cromomicinas
Descriptor in Portuguese: Cromomicinas
Descriptor in French: Chromomycine
Entry term(s): Chromomycin
Tree number(s): D09.408.210
Scope note: A complex of several closely related glycosidic antibiotics from Streptomyces griseus. The major component, CHROMOMYCIN A3, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.
Annotation: antineoplastic antibiotics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 73(72)
DeCS UI: 23195
Descriptor UI: D002865
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2004/07/07
Chromomycins - Preferred
Concept UI M0004396
Scope note A complex of several closely related glycosidic antibiotics from Streptomyces griseus. The major component, CHROMOMYCIN A3, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.
Preferred term Chromomycins
Chromomycin - Narrower
Concept UI M0004397
Preferred term Chromomycin



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