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Descriptor English: Endorphins
Descriptor Spanish: Endorfinas
Descriptor Portuguese: Endorfinas
Descriptor French: Endorphines
Entry term(s): Endorphin
Tree number(s): D12.644.400.575.241
D12.776.631.650.575.241
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004723
Scope note: One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; OPIOID PEPTIDES is used for the broader group.
Annotation:
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Neurotransmitter Agents
Previous Indexing: Nerve Tissue Proteins (1966-Jul 1977)
Peptides (1966-Jul 1977)
Public MeSH Note: 78; was indexed under PEPTIDES Aug-Dec 1977
History Note: 78(Aug 77); was see under PEPTIDES Aug-Dec 1977
Related: Receptors, Opioid MeSH
DeCS ID: 23267
Unique ID: D004723
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1977/05/16
Revision Date: 2015/11/23
Endorphins - Preferred
Concept UI M0007424
Scope note One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; OPIOID PEPTIDES is used for the broader group.
Preferred term Endorphins
Entry term(s) Endorphin



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