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Descriptor English: Immunoglobulin Constant Regions
Descriptor Spanish: Regiones Constantes de Inmunoglobulina
Descriptor regiones constantes de las inmunoglobulinas
Entry term(s) regiones constantes de las Ig
región constante de la inmunoglobulina
Scope note: Los dominios de las moléculas de inmunoglobulinas que son invariables en su secuencia de aminoácidos dentro de cualquier clase o subclase de inmunoglobulina. Confieren funciones biológicas y estructurales a las inmunoglobulinas. Cada una de ellas tanto en las cadenas ligeras como pesadas comprende la mitad C-terminal del FRAGMENTO FAB DE LA INMUNOGLOBULINA y dos o tres de ellos componen el resto de las cadenas pesadas (la totalidad del FRAGMENTO FC DE LA INMUNOGLOBULINA).
Descriptor Portuguese: Regiões Constantes de Imunoglobulina
Descriptor French: Régions constantes des immunoglobulines
Entry term(s): Constant Region, Ig
Constant Region, Immunoglobulin
Constant Regions, Ig
Constant Regions, Immunoglobulin
Ig Constant Regions
Immunoglobulin Constant Region
Regions, Ig Constant
Tree number(s): D12.776.124.486.485.538
D12.776.124.790.651.538
D12.776.377.715.548.538
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007127
Scope note: The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Previous Indexing: Gamma Globulins (1966-1971)
Immunoglobulin Allotypes (1975-1978)
Immunoglobulins (1972-1978)
Immunoglobulins, Fc (1973)
specific immunoglobulin fragment (1973-1978)
Public MeSH Note: 2006; see IMMUNOGLOBULIN CONSTANT REGION 1988-2005, see IMMUNOGLOBULINS 1979-1987; for CONSTANT REGION IG see IMMUNOGLOBULIN CONSTANT REGION 1979-1991
Online Note: use IMMUNOGLOBULIN CONSTANT REGION to search CONSTANT REGION, IG 1979-91
History Note: 2006 (1979)
Entry Version: IG CONSTANT REGIONS
Related: Immunoglobulin Domains MeSH
DeCS ID: 23325
Unique ID: D007127
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1978/03/17
Revision Date: 2019/07/05
Immunoglobulin Constant Regions - Preferred
Concept UI M0011105
Scope note The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)
Preferred term Immunoglobulin Constant Regions
Entry term(s) Constant Region, Ig
Constant Region, Immunoglobulin
Constant Regions, Ig
Constant Regions, Immunoglobulin
Ig Constant Regions
Immunoglobulin Constant Region
Regions, Ig Constant



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