| Descriptor English: | Saralasin | ||||||
| Descriptor Spanish: |
Saralasina
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| Descriptor Portuguese: | Saralasina | ||||||
| Descriptor French: | Saralasine | ||||||
| Entry term(s): |
(Sar(1),Ala(8))ANGII (Sar1,Val5,Ala8)Angiotensin II 1 Sar 8 Ala Angiotensin II 1 Sarcosine 8 Alanine Angiotensin II 1-Sar-8-Ala Angiotensin II 1-Sarcosine-8-Alanine Angiotensin II Angiotensin II, 1-Sar-8-Ala Angiotensin II, 1-Sarcosine-8-Alanine Angiotensin II, Sar(1)-Ala(8)- Angiotensin II, Sarcosyl(1)-Alanine(8)- Anhydrous Saralasin Acetate Hydrated Saralasin Acetate Sar-Arg-Val-Tyr-Val-His-Pro-Ala Saralasin Acetate Saralasin Acetate, Anhydrous Saralasin Acetate, Hydrated |
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| Tree number(s): |
D12.644.456.073.041.800 D23.469.050.050.050.700 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D012504 | ||||||
| Scope note: | An octapeptide analog of angiotensin II (bovine) with amino acids 1 and 8 replaced with sarcosine and alanine, respectively. It is a highly specific competitive inhibitor of angiotensin II that is used in the diagnosis of HYPERTENSION. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Angiotensin II Type 1 Receptor Blockers |
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| Registry Number: | H2AFV2HE66 | ||||||
| CAS Type 1 Name: | Angiotensin II, 1-(N-methylglycine)-5-L-valine-8-L-alanine- | ||||||
| Previous Indexing: |
Alanine (1974) Angiotensin II (1974) Sarcosine (1974) |
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| Public MeSH Note: | 1984; see ANGIOTENSIN II 1978-83; 1-SARCOSINE-8-ALANINE ANGIOTENSIN II was indexed under ANGIOTENSIN II 1975-77 |
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| History Note: | 1984(1978) |
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| DeCS ID: | 23456 | ||||||
| Unique ID: | D012504 | ||||||
| NLM Classification: | QU 68 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1984/01/01 | ||||||
| Date of Entry: | 1974/11/19 | ||||||
| Revision Date: | 2014/06/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Saralasin
- Preferred
Saralasin Acetate
- Narrower
Saralasin Acetate, Anhydrous
- Narrower
| Concept UI |
M0019423 |
| Scope note | An octapeptide analog of angiotensin II (bovine) with amino acids 1 and 8 replaced with sarcosine and alanine, respectively. It is a highly specific competitive inhibitor of angiotensin II that is used in the diagnosis of HYPERTENSION. |
| Preferred term | Saralasin |
| Entry term(s) |
(Sar(1),Ala(8))ANGII (Sar1,Val5,Ala8)Angiotensin II 1 Sar 8 Ala Angiotensin II 1 Sarcosine 8 Alanine Angiotensin II 1-Sar-8-Ala Angiotensin II 1-Sarcosine-8-Alanine Angiotensin II Angiotensin II, 1-Sar-8-Ala Angiotensin II, 1-Sarcosine-8-Alanine Angiotensin II, Sar(1)-Ala(8)- Angiotensin II, Sarcosyl(1)-Alanine(8)- Sar-Arg-Val-Tyr-Val-His-Pro-Ala |
| Concept UI |
M0019422 |
| Preferred term | Saralasin Acetate |
| Entry term(s) |
Hydrated Saralasin Acetate Saralasin Acetate, Hydrated |
| Concept UI |
M0329698 |
| Preferred term | Saralasin Acetate, Anhydrous |
| Entry term(s) |
Anhydrous Saralasin Acetate |
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