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Descriptor English: Angiotensin II
Descriptor Spanish: Angiotensina II
Descriptor angiotensina II
Entry term(s) angiotensina II Ile(5)-
angiotensina II Val(5)-
Scope note: Este octapéptido es un potente vasoconstrictor, aunque inestable. Se produce a partir de la ANGIOTENSINA I, por acción de la ENZIMA CONVERSORA DE ANGIOTENSINA, al eliminar dos aminoácidos del extremo C-terminal. El aminoácido situado en la posición 5 varía entre diferentes especies. Para inhibir el efecto vasoconstrictor e hipertensivo de la angiotensina II, a menudo se trata a los pacientes con INHIBIDORES DE LA ECA o con BLOQUEANTES DEL RECEPTOR DE TIPO 1 DE LA ANGIOTENSINA II.
Descriptor Portuguese: Angiotensina II
Descriptor French: Angiotensine-II
Entry term(s): 5 L Isoleucine Angiotensin II
5-L-Isoleucine Angiotensin II
ANG-(1-8)Octapeptide
Angiotensin II, 5-L-Isoleucine
Angiotensin II, Ile(5)-
Angiotensin II, Isoleucine(5)-
Angiotensin II, Val(5)-
Angiotensin II, Valine(5)-
Angiotensin-(1-8) Octapeptide
Isoleucine(5)-Angiotensin
Isoleucyl(5)-Angiotensin II
Valyl(5)-Angiotensin II
Tree number(s): D06.472.699.094.078
D12.644.400.070.078
D12.644.456.073.041
D12.644.548.058.078
D12.776.631.650.070.078
D23.469.050.050.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000804
Scope note: An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Vasoconstrictor Agents
Registry Number: 11128-99-7
CAS Type 1 Name: Angiotensin II
Public MeSH Note: 1974; see ANGIOTENSIN 1971-1973, see ANGIOTENSIN 1967-1970; ANGIOTENSIN was heading 1964-1978, was HYPERTENSIN 1963 (HYPERTENSIN see ANGIOTENSIN 1964-1965, see ANGIOTENSIN AMIDE 1966-1973); ANGIOTENSIN II, ILE(5)- was indexed under ANGIOTENSIN II 1981-1999, and ISOLEUCINE 1975-1981
History Note: 1974(1963); for ANGIOTENSIN II, ILE(5)- use ANGIOTENSIN II (NM) 1974-1999
Related: Renin-Angiotensin System MeSH
DeCS ID: 22334
Unique ID: D000804
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05
Angiotensin II - Preferred
Concept UI M0001202
Scope note An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
Preferred term Angiotensin II
Entry term(s) ANG-(1-8)Octapeptide
Angiotensin-(1-8) Octapeptide
Angiotensin II, Val(5)- - Narrower
Concept UI M0001205
Preferred term Angiotensin II, Val(5)-
Entry term(s) Angiotensin II, Valine(5)-
Valyl(5)-Angiotensin II
Angiotensin II, Ile(5)- - Narrower
Concept UI M0055996
Preferred term Angiotensin II, Ile(5)-
Entry term(s) 5 L Isoleucine Angiotensin II
5-L-Isoleucine Angiotensin II
Angiotensin II, 5-L-Isoleucine
Angiotensin II, Isoleucine(5)-
Isoleucine(5)-Angiotensin
Isoleucyl(5)-Angiotensin II



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