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Descriptor English: Tunicamycin
Descriptor Spanish: Tunicamicina
Descriptor tunicamicina
Scope note: Antibiótico antiviral que contiene N-acetilglucosamina, obtenido del Streptomyces lysosuperificus. También es activo contra algunas bacterias y hongos, ya que inhibe la glicosilación de las proteínas. La tunicamicina se utiliza como herramienta en el estudio de los mecanismos biosintéticos microbianos.
Descriptor Portuguese: Tunicamicina
Descriptor French: Tunicamycine
Tree number(s): D03.383.742.680.725
D13.570.685.725
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014415
Scope note: An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.
Annotation: an antibiotic; do not use /biosyn unless by living matter
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Antiviral Agents
Registry Number: 11089-65-9
CAS Type 1 Name: Tunicamycin
Previous Indexing: Antibiotics (1966-1978)
Glucosamine (1966-1978)
Public MeSH Note: 87; was see under GLUCOSAMINE 1979-86
History Note: 87(79); was see under GLUCOSAMINE 1979-86
DeCS ID: 23496
Unique ID: D014415
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1978/02/08
Revision Date: 2016/06/01
Tunicamycin - Preferred
Concept UI M0022159
Scope note An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.
Preferred term Tunicamycin



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