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Descriptor English: T-Lymphocytes, Cytotoxic
Descriptor Spanish: Linfocitos T Citotóxicos
Descriptor Portuguese: Linfócitos T Citotóxicos
Descriptor French: Lymphocytes T cytotoxiques
Entry term(s): Cell Mediated Lympholytic Cells
Cell, Cell-Mediated Lympholytic
Cell, TC1
Cell, TC2
Cell-Mediated Lympholytic Cell
Cell-Mediated Lympholytic Cells
Cells, Cell-Mediated Lympholytic
Cells, TC1
Cells, TC2
Cytotoxic T Lymphocyte
Cytotoxic T Lymphocytes
Cytotoxic T-Lymphocyte
Cytotoxic T-Lymphocytes
Lymphocyte, Cytotoxic T
Lymphocytes, Cytotoxic T
Lympholytic Cell, Cell-Mediated
Lympholytic Cells, Cell-Mediated
T Lymphocyte, Cytotoxic
T Lymphocytes, Cytotoxic
T-Lymphocyte, Cytotoxic
TC1 Cell
TC1 Cells
TC2 Cell
TC2 Cells
Tree number(s): A11.118.637.555.283.875
A11.118.637.555.567.550.500.200
A11.118.637.555.567.569.220.200
A11.118.637.555.567.569.500.200
A15.145.229.637.555.283.875
A15.145.229.637.555.567.550.500.200
A15.145.229.637.555.567.569.220.200
A15.145.229.637.555.567.569.500.200
A15.382.490.555.283.875
A15.382.490.555.567.550.500.200
A15.382.490.555.567.569.220.200
A15.382.490.555.567.569.500.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013602
Scope note: Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
Annotation: if subpopulations are discussed, coordinate IM with T-LYMPHOCYTE SUBSETS (IM)
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cytotoxicity, Immunologic (1978-1982)
T Lymphocytes (1973-1982)
Public MeSH Note: 90; was T LYMPHOCYTES, CYTOTOXIC 1983-89
Online Note: use T-LYMPHOCYTES, CYTOTOXIC to search T LYMPHOCYTES, CYTOTOXIC 1983-89
History Note: 90; was T LYMPHOCYTES, CYTOTOXIC 1983-89
Entry Version: T LYMPHOCYTES CYTOTOX
DeCS ID: 23531
Unique ID: D013602
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/04/29
Revision Date: 2020/05/27
T-Lymphocytes, Cytotoxic - Preferred
Concept UI M0020989
Scope note Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
Preferred term T-Lymphocytes, Cytotoxic
Entry term(s) Cell Mediated Lympholytic Cells
Cell, Cell-Mediated Lympholytic
Cell-Mediated Lympholytic Cell
Cell-Mediated Lympholytic Cells
Cells, Cell-Mediated Lympholytic
Cytotoxic T Lymphocyte
Cytotoxic T Lymphocytes
Cytotoxic T-Lymphocyte
Cytotoxic T-Lymphocytes
Lymphocyte, Cytotoxic T
Lymphocytes, Cytotoxic T
Lympholytic Cell, Cell-Mediated
Lympholytic Cells, Cell-Mediated
T Lymphocyte, Cytotoxic
T Lymphocytes, Cytotoxic
T-Lymphocyte, Cytotoxic
TC2 Cells - Narrower
Concept UI M0373138
Preferred term TC2 Cells
Entry term(s) Cell, TC2
Cells, TC2
TC2 Cell
TC1 Cells - Narrower
Concept UI M0373137
Preferred term TC1 Cells
Entry term(s) Cell, TC1
Cells, TC1
TC1 Cell



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