| Descriptor English: | T-Lymphocytes, Cytotoxic | ||||||
| Descriptor Spanish: |
Linfocitos T Citotóxicos
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| Descriptor Portuguese: | Linfócitos T Citotóxicos | ||||||
| Descriptor French: | Lymphocytes T cytotoxiques | ||||||
| Entry term(s): |
Cell Mediated Lympholytic Cells Cell, Cell-Mediated Lympholytic Cell, TC1 Cell, TC2 Cell-Mediated Lympholytic Cell Cell-Mediated Lympholytic Cells Cells, Cell-Mediated Lympholytic Cells, TC1 Cells, TC2 Cytotoxic T Cells Cytotoxic T Lymphocyte Cytotoxic T Lymphocytes Cytotoxic T-Lymphocyte Cytotoxic T-Lymphocytes Lymphocyte, Cytotoxic T Lymphocytes, Cytotoxic T Lympholytic Cell, Cell-Mediated Lympholytic Cells, Cell-Mediated T Lymphocyte, Cytotoxic T Lymphocytes, Cytotoxic T-Lymphocyte, Cytotoxic TC1 Cell TC1 Cells TC2 Cell TC2 Cells |
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| Tree number(s): |
A11.118.637.555.283.875 A11.118.637.555.567.550.500.200 A11.118.637.555.567.569.220.200 A11.118.637.555.567.569.500.200 A15.145.229.637.555.283.875 A15.145.229.637.555.567.550.500.200 A15.145.229.637.555.567.569.220.200 A15.145.229.637.555.567.569.500.200 A15.382.490.555.283.875 A15.382.490.555.567.550.500.200 A15.382.490.555.567.569.220.200 A15.382.490.555.567.569.500.200 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013602 | ||||||
| Scope note: | Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2. |
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| Annotation: | if subpopulations are discussed, coordinate IM with T-LYMPHOCYTE SUBSETS (IM) |
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| Allowable Qualifiers: |
CH chemistry CL classification CY cytology DE drug effects EN enzymology IM immunology ME metabolism MI microbiology PA pathology PH physiology PS parasitology RE radiation effects TR transplantation UL ultrastructure VI virology |
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| Previous Indexing: |
Cytotoxicity, Immunologic (1978-1982) T Lymphocytes (1973-1982) |
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| Public MeSH Note: | 90; was T LYMPHOCYTES, CYTOTOXIC 1983-89 |
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| Online Note: | use T-LYMPHOCYTES, CYTOTOXIC to search T LYMPHOCYTES, CYTOTOXIC 1983-89 |
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| History Note: | 90; was T LYMPHOCYTES, CYTOTOXIC 1983-89 |
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| Entry Version: | T LYMPHOCYTES CYTOTOX |
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| DeCS ID: | 23531 | ||||||
| Unique ID: | D013602 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1983/01/01 | ||||||
| Date of Entry: | 1982/04/29 | ||||||
| Revision Date: | 2020/05/27 |
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ANATOMY
Cells [A11]Cells -
ANATOMY
Cells [A11]Cells -
ANATOMY
Cells [A11]Cells
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T-Lymphocytes, Cytotoxic
- Preferred
TC2 Cells
- Narrower
TC1 Cells
- Narrower
| Concept UI |
M0020989 |
| Scope note | Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2. |
| Preferred term | T-Lymphocytes, Cytotoxic |
| Entry term(s) |
Cell Mediated Lympholytic Cells Cell, Cell-Mediated Lympholytic Cell-Mediated Lympholytic Cell Cell-Mediated Lympholytic Cells Cells, Cell-Mediated Lympholytic Cytotoxic T Cells Cytotoxic T Lymphocyte Cytotoxic T Lymphocytes Cytotoxic T-Lymphocyte Cytotoxic T-Lymphocytes Lymphocyte, Cytotoxic T Lymphocytes, Cytotoxic T Lympholytic Cell, Cell-Mediated Lympholytic Cells, Cell-Mediated T Lymphocyte, Cytotoxic T Lymphocytes, Cytotoxic T-Lymphocyte, Cytotoxic |
| Concept UI |
M0373138 |
| Preferred term | TC2 Cells |
| Entry term(s) |
Cell, TC2 Cells, TC2 TC2 Cell |
| Concept UI |
M0373137 |
| Preferred term | TC1 Cells |
| Entry term(s) |
Cell, TC1 Cells, TC1 TC1 Cell |
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