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Descriptor English: Isotretinoin
Descriptor Spanish: Isotretinoína
Descriptor isotretinoína
Entry term(s) ácido 13-cis-retinoico
Scope note: Agente dermatológico tópico que se utiliza en el tratamiento del ACNÉ VULGAR y otras muchas enfermedades de la piel. El fármaco tiene efecto teratogénico y otras reacciones adversas.
Descriptor Portuguese: Isotretinoína
Descriptor French: Isotrétinoïne
Entry term(s): 13 cis Retinoic Acid
13-cis-Retinoic Acid
Accutane
Isotretinoin Zinc Salt, 13 cis Isomer
Isotretinoin Zinc Salt, 13-cis-Isomer
Ro 4 3780
Ro 4-3780
Ro 43780
Roaccutane
Tree number(s): D02.455.326.271.665.202.495.325
D02.455.426.392.368.367.379.249.700.325
D02.455.849.131.495.325
D23.767.261.700.325
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015474
Scope note: A topical dermatologic agent that is used in the treatment of ACNE VULGARIS and several other skin diseases. The drug has teratogenic and other adverse effects.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Dermatologic Agents
Teratogens
Registry Number: EH28UP18IF
CAS Type 1 Name: Retinoic acid, 13-cis-
Previous Indexing: Dermatologic Agents (1975-1988)
Keratolytic Agents (1975-1988)
Tretinoin (1975-1988)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23705
Unique ID: D015474
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/06/09
Revision Date: 2013/07/08
Isotretinoin - Preferred
Concept UI M0023831
Scope note A topical dermatologic agent that is used in the treatment of ACNE VULGARIS and several other skin diseases. The drug has teratogenic and other adverse effects.
Preferred term Isotretinoin
Entry term(s) 13 cis Retinoic Acid
13-cis-Retinoic Acid
Isotretinoin Zinc Salt, 13-cis-Isomer - Narrower
Concept UI M0329538
Preferred term Isotretinoin Zinc Salt, 13-cis-Isomer
Entry term(s) Isotretinoin Zinc Salt, 13 cis Isomer
Roaccutane - Narrower
Concept UI M0023832
Preferred term Roaccutane
Accutane - Related but not broader or narrower
Concept UI M0023833
Preferred term Accutane
Ro 4-3780 - Narrower
Concept UI M0351975
Preferred term Ro 4-3780
Entry term(s) Ro 4 3780
Ro 43780



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