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Descriptor English: Prostaglandin D2
Descriptor Spanish: Prostaglandina D2
Descriptor prostaglandina D2
Entry term(s) 11-deshidroprostaglandina F2 alfa
PGD2
Scope note: El principal metabolito del ácido araquidónico por la vía de la ciclooxigenasa Se libera con la activación de las células cebadas y es sintetizado también por los macrófagos alveolares. Entre sus muchas acciones biológicas, las más importantes son la de broncoconstrictor, inhibidor del factor activador plaquetario y efectos citotóxicos.
Descriptor Portuguese: Prostaglandina D2
Descriptor French: Prostaglandine D2
Entry term(s): 11 Dehydroprostaglandin F2 alpha
11 Dehydroprostaglandin F2alpha
11-Dehydroprostaglandin F2 alpha
11-Dehydroprostaglandin F2alpha
D2, Prostaglandin
F2 alpha, 11-Dehydroprostaglandin
F2alpha, 11-Dehydroprostaglandin
PGD2
alpha, 11-Dehydroprostaglandin F2
Tree number(s): D10.251.355.255.550.200.200
D23.469.050.175.725.200.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015230
Scope note: The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: RXY07S6CZ2
CAS Type 1 Name: Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9alpha,13E,15S)-
Previous Indexing: Prostaglandins (1966-1977)
Prostaglandins D (1978-1988)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23804
Unique ID: D015230
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/12
Revision Date: 2015/06/08
Prostaglandin D2 - Preferred
Concept UI M0023403
Scope note The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Preferred term Prostaglandin D2
Entry term(s) 11 Dehydroprostaglandin F2 alpha
11 Dehydroprostaglandin F2alpha
11-Dehydroprostaglandin F2 alpha
11-Dehydroprostaglandin F2alpha
D2, Prostaglandin
F2 alpha, 11-Dehydroprostaglandin
F2alpha, 11-Dehydroprostaglandin
PGD2
alpha, 11-Dehydroprostaglandin F2



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