| Descriptor English: | Procyclidine | ||||
| Descriptor Spanish: | 
                                Prociclidina                                        
                                        
                                                                                                                            
                                            
  | ||||
| Descriptor Portuguese: | Prociclidina | ||||
| Descriptor French: | Procyclidine | ||||
| Entry term(s): | 
                                    Arpicolin Hydrochloride, Procyclidine Kemadren Kemadrin Mucinil Osnervan Procyclid Procyclidine Hydrochloride Tricyclamol  | 
                                            ||||
| Tree number(s): | 
                                        D03.383.773.728 | 
                                ||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011352 | ||||
| Scope note: | A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism. | 
                                    ||||
| Annotation: | a central muscle relaxant | 
                                    ||||
| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
                                            ||||
| Pharm Action: | 
                                                                                                    Antiparkinson Agents Muscarinic Antagonists  | 
                                    ||||
| Registry Number: | C6QE1Q1TKR | ||||
| CAS Type 1 Name: | 1-Pyrrolidinepropanol, alpha-cyclohexyl-alpha-phenyl- | ||||
| Public MeSH Note: | 91; was see under PYRROLIDINES 1966-90 | 
                                                ||||
| History Note: | 91(66); was see under PYRROLIDINES 1966-90 | 
                                                ||||
| DeCS ID: | 24294 | ||||
| Unique ID: | D011352 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1991/01/01 | ||||
| Date of Entry: | 1999/01/01 | ||||
| Revision Date: | 2017/05/24 | 
- 
                                    
- 
                                        CHEMICALS AND DRUGS
 
Heterocyclic Compounds [D03]Heterocyclic Compounds 
| 
                                                             | 
                                
                        
                                                                    
                        Procyclidine                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Tricyclamol                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Procyclidine Hydrochloride                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Kemadren                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Mucinil                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Procyclid                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Kemadrin                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Arpicolin                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0017638 | 
                                
| Scope note | A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism. | 
| Preferred term | Procyclidine | 
| Concept UI | 
                                        
                                        M0017639 | 
                                
| Preferred term | Tricyclamol | 
| Concept UI | 
                                        
                                        M0475950 | 
                                
| Preferred term | Procyclidine Hydrochloride | 
| Entry term(s) | 
                                        
                                                                                            Hydrochloride, Procyclidine                                                 | 
                                
| Concept UI | 
                                        
                                        M0475952 | 
                                
| Preferred term | Kemadren | 
| Concept UI | 
                                        
                                        M0475953 | 
                                
| Preferred term | Mucinil | 
| Concept UI | 
                                        
                                        M0475954 | 
                                
| Preferred term | Procyclid | 
| Concept UI | 
                                        
                                        M0017637 | 
                                
| Preferred term | Kemadrin | 
| Entry term(s) | 
                                        
                                                                                            Osnervan                                                 | 
                                
| Concept UI | 
                                        
                                        M0475951 | 
                                
| Preferred term | Arpicolin | 
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