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Descriptor English: Enalaprilat
Descriptor Spanish: Enalaprilato
Descriptor enalaprilato
Entry term(s) 1-(N-((S)-1-carboxi-3-fenilpropil)-L-alanil)-L-prolina dihidratada
MK 422
MK-422
Vasotec
Xanef
citrato de enalaprilato anhidro
enalaprilato anhidro
enalaprilato dihidratado
isómero (R) de enalaprilato anhidro
pres iv
ácido enalaprílico
Scope note: El metabolito activo del ENALAPRIL y un potente inhibidor de la enzima convertidora de la angiotensina que se administra por vía intravenosa. Es un agente efectivo en el tratamiento de la hipertensión esencial y tiene efectos hemodinámicos beneficiosos en la insuficiencia cardíaca. El fármaco produce vasodilatación renal con incremento en la excreción de sodio.
Descriptor Portuguese: Enalaprilato
Descriptor French: Énalaprilate
Entry term(s): 1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
Enalaprilat Anhydrous
Enalaprilat Citrate, Anhydrous
Enalaprilat Dihydrate
Enalaprilat, (R)-Isomer, Anhydrous
Enalaprilic Acid
MK 422
MK-422
MK422
Pres iv
Vasotec
Xanef
Tree number(s): D12.644.456.345.360.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015773
Scope note: The active metabolite of ENALAPRIL and one of the potent, intravenously administered, ANGIOTENSIN-CONVERTING ENZYME INHIBITORS. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. The drug produces renal vasodilation with an increase in sodium excretion.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Registry Number: GV0O7ES0R3
CAS Type 1 Name: L-Proline, N-((1S)-1-carboxy-3-phenylpropyl)-L-alanyl-
Previous Indexing: Dipeptides (1966-1985)
Enalapril (1986-1989)
History Note: 1990
DeCS ID: 24621
Unique ID: D015773
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/07/19
Revision Date: 2018/05/21
Enalaprilat - Preferred
Concept UI M0024167
Scope note The active metabolite of ENALAPRIL and one of the potent, intravenously administered, ANGIOTENSIN-CONVERTING ENZYME INHIBITORS. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. The drug produces renal vasodilation with an increase in sodium excretion.
Preferred term Enalaprilat
Enalaprilic Acid - Related but not broader or narrower
Concept UI M000638637
Preferred term Enalaprilic Acid
Enalaprilat Dihydrate - Related but not broader or narrower
Concept UI M000629535
Preferred term Enalaprilat Dihydrate
Enalaprilat Citrate, Anhydrous - Narrower
Concept UI M0329457
Preferred term Enalaprilat Citrate, Anhydrous
Enalaprilat, (R)-Isomer, Anhydrous - Narrower
Concept UI M0329454
Preferred term Enalaprilat, (R)-Isomer, Anhydrous
Pres iv - Narrower
Concept UI M0485301
Preferred term Pres iv
Vasotec - Narrower
Concept UI M0363632
Preferred term Vasotec
Enalaprilat Anhydrous - Narrower
Concept UI M0329455
Preferred term Enalaprilat Anhydrous
Xanef - Narrower
Concept UI M0485300
Preferred term Xanef
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate - Narrower
Concept UI M000642353
Preferred term 1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
MK-422 - Narrower
Concept UI M0363630
Preferred term MK-422
Entry term(s) MK 422
MK422



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