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Descriptor English: Ion Channel Gating
Descriptor Spanish: Activación del Canal Iónico
Descriptor activación de canales iónicos
Scope note: Apertura o cierre de canales iónicos como consecuencia de un estímulo. Dicho estímulo puede ser un cambio del potencial de membrana (activación por voltaje), drogas o compuestos químicos transmisores (activación por ligando), o una deformación mecánica. Se piensa que la activación conlleva cambios en la conformación de los canales iónicos, alterando selectivamente la permeabilidad.
Descriptor Portuguese: Ativação do Canal Iônico
Descriptor French: Ouverture et fermeture des portes des canaux ioniques
Entry term(s): Gating, Ion Channel
Gatings, Ion Channel
Ion Channel Gatings
Tree number(s): G02.111.820.400
G04.835.400
G07.265.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015640
Scope note: The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
Annotation: do not confuse with SENSORY GATING
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Electric Conductivity (1966-1989)
Electrophysiology (1966-1989)
Ion Channels (1979-1989)
Membrane Potentials (1966-1989)
Public MeSH Note: 90
History Note: 90
DeCS ID: 24753
Unique ID: D015640
NLM Classification: QU 55.7
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/06/19
Revision Date: 2016/06/17
Ion Channel Gating - Preferred
Concept UI M0023977
Scope note The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
Preferred term Ion Channel Gating
Entry term(s) Gating, Ion Channel
Gatings, Ion Channel
Ion Channel Gatings



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