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Descriptor English: Adjuvants, Immunologic
Descriptor Spanish: Adyuvantes Inmunológicos
Descriptor adyuvantes inmunitarios
Entry term(s) adyuvante inmunológico
adyuvantes inmunológicos
inmunoactivadores
inmunoadyuvante
inmunoadyuvantes
inmunoestimulante
inmunoestimulantes
inmunopotenciador
inmunopotenciadores
Scope note: Sustancias que incrementan, estimulan, activan, potencian o modulan la respuesta inmunitaria tanto a nivel celular como humoral. Los agentes clásicos (adyuvante de Freund, BCG, Corynebacterium parvum y otros) contienen antígenos bacterianos. Algunos son endógenos (por ejemplo: histamina, interferón, factor de transferencia, tuftsina, interleucina-1). Su modo de acción puede ser inespecífico, de modo que generan un incremento en la respuesta inmunitaria frente a una gran variedad de antígenos, o específico de antígenos, es decir, que afecta a un tipo restringido de respuesta inmune frente a un pequeño grupo de antígenos. La eficacia terapéutica de muchos modificadores de la respuesta biológica se relaciona con su especificidad antigénica.
Descriptor Portuguese: Adjuvantes Imunológicos
Descriptor French: Adjuvants immunologiques
Entry term(s): Adjuvant, Immunologic
Adjuvant, Immunological
Adjuvants, Immunological
Immunoactivators
Immunoadjuvant
Immunoadjuvants
Immunologic Adjuvant
Immunologic Adjuvants
Immunological Adjuvant
Immunological Adjuvants
Immunopotentiator
Immunopotentiators
Immunostimulant
Immunostimulants
Tree number(s): D27.505.696.477.067
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000276
Scope note: Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 65
History Note: 65
Entry Version: ADJUVANTS IMMUNOL
Related: Adjuvants, Pharmaceutic MeSH
DeCS ID: 27905
Unique ID: D000276
NLM Classification: QW 800
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Adjuvants, Immunologic - Preferred
Concept UI M0000431
Scope note Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Preferred term Adjuvants, Immunologic
Entry term(s) Adjuvant, Immunologic
Adjuvant, Immunological
Adjuvants, Immunological
Immunoactivators
Immunoadjuvant
Immunoadjuvants
Immunologic Adjuvant
Immunologic Adjuvants
Immunological Adjuvant
Immunological Adjuvants
Immunopotentiator
Immunopotentiators
Immunostimulant
Immunostimulants



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