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Descriptor English: Coformycin
Descriptor Spanish: Coformicina
Descriptor coformicina
Scope note: Antibiótico ribonucleósido sinérgico e inhibidor de la adenosina desaminasa, aislado de la Nocardia interforma y del Streptomyces kaniharaensis. Está propuesto como antineoplásico sinérgico e inmunosupresor.
Descriptor Portuguese: Coformicina
Descriptor French: Coformycine
Tree number(s): D03.383.742.680.350.200
D13.570.685.350.200
D13.570.800.410.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003070
Scope note: A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is proposed as an antineoplastic synergist and immunosuppressant.
Annotation: an enzyme inhib & antineoplastic antibiotic
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Enzyme Inhibitors
Immunosuppressive Agents
Registry Number: 11033-22-0
CAS Type 1 Name: Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-
Previous Indexing: Azepines (1966-1978)
Nucleosides (1966-1970)
Ribonucleosides (1971-1978)
Public MeSH Note: 90; was see under RIBONUCLEOSIDES 1979-89
History Note: 90(79); was see under RIBONUCLEOSIDES 1979-89
DeCS ID: 27961
Unique ID: D003070
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1977/12/08
Revision Date: 2016/05/28
Coformycin - Preferred
Concept UI M0004720
Scope note A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is proposed as an antineoplastic synergist and immunosuppressant.
Preferred term Coformycin



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