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Descriptor English: Leucovorin
Descriptor Spanish: Leucovorina
Descriptor leucovorina
Entry term(s) N(5)-formiltetrahidrofolato
factor citrovorum
leucovorina cálcica
ácido folínico
Scope note: Metabolito activo del ÁCIDO FÓLICO. La leucovorina se utiliza principalmente como antídoto de los ANTAGONISTAS DEL ÁCIDO FÓLICO.
Descriptor Portuguese: Leucovorina
Descriptor French: Leucovorine
Entry term(s): 5 Formyltetrahydrofolate
5 Formyltetrahydropteroylglutamate
5-Formyltetrahydrofolate
5-Formyltetrahydropteroylglutamate
Acid, Folinic
Calcium Folinate
Calcium Leucovorin
Citrovorum Factor
Factor, Citrovorum
Folinate, Calcium
Folinic Acid
Folinic Acid SF
Folinic Acid-SF
Leucovorin, (D)-Isomer
Leucovorin, (DL)-Isomer
Leucovorin, (R)-Isomer
Leucovorin, Calcium
Leucovorin, Calcium (1:1) Salt
Leucovorin, Calcium (1:1) Salt, (DL)-Isomer
Leucovorin, Calcium (1:1) Salt, Pentahydrate
Leucovorin, Monosodium Salt
Leukovorin
Leukovorum
Monosodium Salt Leucovorin
N(5)-Formyltetrahydrofolate
Wellcovorin
Tree number(s): D03.633.100.733.631.400.800.350.450
D08.211.840.300.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002955
Scope note: The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
Annotation: deficiency: coordinate LEUCOVORIN /defic (IM) with FOLIC ACID DEFICIENCY (IM)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidotes
Vitamin B Complex
Registry Number: Q573I9DVLP
CAS Type 1 Name: L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
Public MeSH Note: 90; was CITROVORUM FACTOR 1964-89
Online Note: use LEUCOVORIN to search CITROVORUM FACTOR 1966-89
History Note: 90; was CITROVORUM FACTOR 1964-89
DeCS ID: 28238
Unique ID: D002955
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Leucovorin - Preferred
Concept UI M0004519
Scope note The active metabolite of FOLIC ACID. Leucovorin is used principally as an antidote to FOLIC ACID ANTAGONISTS.
Preferred term Leucovorin
Entry term(s) Acid, Folinic
Folinic Acid
Folinic Acid SF
Folinic Acid-SF
Leukovorin
Leukovorum
Leucovorin, (DL)-Isomer - Narrower
Concept UI M0330668
Preferred term Leucovorin, (DL)-Isomer
Citrovorum Factor - Narrower
Concept UI M0004520
Preferred term Citrovorum Factor
Entry term(s) Calcium Folinate
Calcium Leucovorin
Factor, Citrovorum
Folinate, Calcium
Leucovorin, Calcium
Leucovorin, (R)-Isomer - Narrower
Concept UI M0330674
Preferred term Leucovorin, (R)-Isomer
Leucovorin, Calcium (1:1) Salt - Narrower
Concept UI M0330667
Preferred term Leucovorin, Calcium (1:1) Salt
Leucovorin, Calcium (1:1) Salt, Pentahydrate - Narrower
Concept UI M0330671
Preferred term Leucovorin, Calcium (1:1) Salt, Pentahydrate
Leucovorin, Monosodium Salt - Narrower
Concept UI M0330669
Preferred term Leucovorin, Monosodium Salt
Entry term(s) Monosodium Salt Leucovorin
N(5)-Formyltetrahydrofolate - Narrower
Concept UI M0004521
Preferred term N(5)-Formyltetrahydrofolate
Entry term(s) 5 Formyltetrahydrofolate
5 Formyltetrahydropteroylglutamate
5-Formyltetrahydrofolate
5-Formyltetrahydropteroylglutamate
Wellcovorin - Narrower
Concept UI M0369300
Preferred term Wellcovorin
Leucovorin, (D)-Isomer - Narrower
Concept UI M0330670
Preferred term Leucovorin, (D)-Isomer
Leucovorin, Calcium (1:1) Salt, (DL)-Isomer - Narrower
Concept UI M0330672
Preferred term Leucovorin, Calcium (1:1) Salt, (DL)-Isomer



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