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Descriptor English: Fluoxetine
Descriptor Spanish: Fluoxetina
Descriptor Portuguese: Fluoxetina
Descriptor French: Fluoxétine
Entry term(s): Fluoxetin
Fluoxetine Hydrochloride
Lilly 110140
Lilly-110140
Lilly110140
N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
Prozac
Sarafem
Tree number(s): D02.092.831.280
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005473
Scope note: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Serotonin Uptake Inhibitors
Antidepressive Agents, Second-Generation
Cytochrome P-450 CYP2D6 Inhibitors
Registry Number: 01K63SUP8D
CAS Type 1 Name: Benzenepropanamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, (+-)-
Previous Indexing: Phenyl Ethers (1974-1978)
Propylamines (1966-1978)
Public MeSH Note: 90; was FLUOXETIN see under PROPYLAMINES 1979-88; was FLUOXETIN 1989
Online Note: use FLUOXETINE to search FLUOXETIN 1979-89
History Note: 90(79); was FLUOXETIN see under PROPYLAMINES 1979-88; was FLUOXETIN 1989
DeCS ID: 28248
Unique ID: D005473
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1977/12/09
Revision Date: 2014/06/17
Fluoxetine - Preferred
Concept UI M0008635
Scope note The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
Preferred term Fluoxetine
Entry term(s) Fluoxetin
N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
Lilly-110140 - Narrower
Concept UI M0008637
Preferred term Lilly-110140
Entry term(s) Lilly 110140
Lilly110140
Sarafem - Narrower
Concept UI M0496772
Preferred term Sarafem
Fluoxetine Hydrochloride - Narrower
Concept UI M0351280
Preferred term Fluoxetine Hydrochloride
Prozac - Narrower
Concept UI M0008636
Preferred term Prozac



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