| Descriptor English: | Granulocyte-Macrophage Colony-Stimulating Factor | ||||||
| Descriptor Spanish: |
Factor Estimulante de Colonias de Granulocitos y Macrófagos
| ||||||
| Descriptor Portuguese: | Fator Estimulador de Colônias de Granulócitos e Macrófagos | ||||||
| Descriptor French: | Facteur de stimulation des colonies de granulocytes et de macrophages | ||||||
| Entry term(s): |
CSF-2 CSF-GM Cell-Stimulating Factor, Histamine-Producing Colony Stimulating Factor, Granulocyte Macrophage Colony-Stimulating Factor, Granulocyte-Macrophage GM-CSF Granulocyte Macrophage Colony Stimulating Factor Histamine Producing Cell Stimulating Factor Histamine-Producing Cell-Stimulating Factor TC-GM-CSF Tumor Cell Human GM Colony Stimulating Factor Tumor-Cell Human GM Colony-Stimulating Factor |
||||||
| Tree number(s): |
D09.400.430.775.300 D12.644.276.374.410.240.375 D12.776.395.240.300 D12.776.467.374.410.240.375 D23.529.374.410.240.375 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016178 | ||||||
| Scope note: | An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. |
||||||
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
||||||
| Registry Number: | 83869-56-1 | ||||||
| CAS Type 1 Name: | Colony-stimulating factor 2 | ||||||
| Previous Indexing: |
Colony-Stimulating Factors (1976-1990) Growth Substances (1966-1990) Interleukin-3 (1981-1987) |
||||||
| Public MeSH Note: | 91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91 |
||||||
| Online Note: | use INTERLEUKIN-3 to search HISTAMINE-PRODUCING CELL-STIMULATING FACTOR 1987-91 |
||||||
| History Note: | 91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91 |
||||||
| Entry Version: | GMCSF |
||||||
| Related: |
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
MeSH | ||||||
| DeCS ID: | 28969 | ||||||
| Unique ID: | D016178 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1990/06/19 | ||||||
| Revision Date: | 2006/07/05 |
-
-
CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
|
|
Granulocyte-Macrophage Colony-Stimulating Factor
- Preferred
| Concept UI |
M0024695 |
| Scope note | An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. |
| Preferred term | Granulocyte-Macrophage Colony-Stimulating Factor |
| Entry term(s) |
CSF-2 CSF-GM Cell-Stimulating Factor, Histamine-Producing Colony Stimulating Factor, Granulocyte Macrophage Colony-Stimulating Factor, Granulocyte-Macrophage GM-CSF Granulocyte Macrophage Colony Stimulating Factor Histamine Producing Cell Stimulating Factor Histamine-Producing Cell-Stimulating Factor TC-GM-CSF Tumor Cell Human GM Colony Stimulating Factor Tumor-Cell Human GM Colony-Stimulating Factor |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
