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Descriptor English: Poly I-C
Descriptor Spanish: Poli I-C
Descriptor poli I-C
Scope note: Inductor del interferón constituido por un ARN sintético, mal apareado y bicatenario. El polímero se produce a partir de una cadena de ácido poliinosínico y otra de ácido policitidílico.
Descriptor Portuguese: Poli I-C
Descriptor French: Poly I-C
Entry term(s): Inosin-Cytidil, Polyribose
Poly I C
Poly(I-C)
Poly(rI).Poly(rC)
Polyinosinic Polycytidylic Acid
Polyinosinic-Polycytidylic Acid
Polyinosinic-Polycytidylic Acid (High MW)
Polyriboinosinic Polyribocytidylic Acid
Polyriboinosinic-Polyribocytidylic Acid
Polyribose Inosin Cytidil
Polyribose Inosin-Cytidil
Tree number(s): D13.695.578.550.560.600
D13.695.578.550.650.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011070
Scope note: Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.
Annotation: do not confuse with POLY I
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antiviral Agents
Interferon Inducers
Registry Number: O84C90HH2L
CAS Type 1 Name: 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1)
Previous Indexing: Interferons/biosynthesis (1966-1970)
Polynucleotides (1966-1970)
Public MeSH Note: 73
History Note: 73(71)
DeCS ID: 29517
Unique ID: D011070
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/03/08
Poly I-C - Preferred
Concept UI M0017148
Scope note Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.
Preferred term Poly I-C
Entry term(s) Inosin-Cytidil, Polyribose
Poly I C
Poly(I-C)
Poly(rI).Poly(rC)
Polyinosinic Polycytidylic Acid
Polyinosinic-Polycytidylic Acid
Polyinosinic-Polycytidylic Acid (High MW)
Polyriboinosinic Polyribocytidylic Acid
Polyriboinosinic-Polyribocytidylic Acid
Polyribose Inosin Cytidil
Polyribose Inosin-Cytidil



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