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Descriptor English: Receptors, sigma
Descriptor Spanish: Receptores sigma
Descriptor receptores sigma
Entry term(s) receptores opioides sigma
receptores sigma opioides
Scope note: Clase de receptores de la superficie celular reconocidos por su perfil farmacológico. Los receptores sigma se consideraron originalmente como receptores opiáceos debido a que se unen a ciertos opioides sintéticos. Sin embargo, tales receptores interactúan también con otras diversas drogas psicoactivas, y su ligando endógeno no se conoce (aunque puede reaccionar con ciertos esteroides endógenos). Los receptores sigma se encuentran en los sistemas inmunitario, endocrino y nervioso, así como en algunos tejidos periféricos.
Descriptor Portuguese: Receptores sigma
Descriptor French: Récepteur sigma
Entry term(s): Opioid Receptors, sigma
Receptor, sigma
Receptors, Opioid, sigma
Receptors, sigma Opioid
sigma Opioid Receptors
sigma Receptor
sigma Receptors
Tree number(s): D12.776.543.750.695.620.775
D12.776.543.750.720.600.610.775
D12.776.543.750.750.555.610.775
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017480
Scope note: A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Endorphin (1981-1992)
Public MeSH Note: 93; SIGMA RECEPTOR was indexed under RECEPTORS, ENDORPHIN 1981-92
Online Note: use RECEPTORS, SIGMA (NM) to search SIGMA RECEPTOR 1981-92
History Note: 93; was SIGMA RECEPTOR (NM) 1981-92
Entry Version: RECEPT SIGMA
DeCS ID: 30546
Unique ID: D017480
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2016/06/17
Receptors, sigma - Preferred
Concept UI M0026516
Scope note A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.
Preferred term Receptors, sigma
Entry term(s) Opioid Receptors, sigma
Receptor, sigma
Receptors, Opioid, sigma
Receptors, sigma Opioid
sigma Opioid Receptors
sigma Receptor
sigma Receptors



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