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Descriptor English: Quinolinic Acid
Descriptor Spanish: Ácido Quinolínico
Descriptor ácido quinolínico
Entry term(s) quinolinato
Scope note: Metabolito del triptofano con un posible papel en las enfermedades neurodegenerativas. Niveles elevados de ácido quinolínico en el líquido cefalorraquídeo se correlacionan significativamente con la gravedad de los déficits neuropsicológicos en pacientes que tienen SIDA.
Descriptor Portuguese: Ácido Quinolínico
Descriptor French: Acide quinolinique
Entry term(s): Quinolinate
Quinolinic Acid, Copper(2+) Salt
Quinolinic Acid, Disodium Salt
Quinolinic Acid, Strontium Salt
Tree number(s): D03.383.725.822.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017378
Scope note: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: analogs & derivatives:Quinolinic Acids
Registry Number: F6F0HK1URN
CAS Type 1 Name: 2,3-Pyridinedicarboxylic acid
Previous Indexing: Quinolinic Acids (1981-1992)
Public MeSH Note: 93; QUINOLINIC ACID was indexed under QUINOLINIC ACIDS 1981-92
Online Note: use QUINOLINIC ACID (NM) to search QUINOLINIC ACID 1981-92
History Note: 93; was QUINOLINIC ACID (NM) 1981-92
DeCS ID: 30582
Unique ID: D017378
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2016/05/31
Quinolinic Acid - Preferred
Concept UI M0026392
Scope note A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
Preferred term Quinolinic Acid
Quinolinic Acid, Strontium Salt - Narrower
Concept UI M0329214
Preferred term Quinolinic Acid, Strontium Salt
Quinolinic Acid, Disodium Salt - Narrower
Concept UI M0329212
Preferred term Quinolinic Acid, Disodium Salt
Quinolinate - Narrower
Concept UI M0373102
Preferred term Quinolinate
Quinolinic Acid, Copper(2+) Salt - Narrower
Concept UI M0329213
Preferred term Quinolinic Acid, Copper(2+) Salt



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