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Descriptor English: Goserelin
Descriptor Spanish: Goserelina
Descriptor goserelina
Entry term(s) goserrelina
Scope note: Agonista sintético de la HORMONA LIBERADORA DE GONADOTROPINAS, de acción prolongada. Se utiliza en el tratamiento de NEOPLASIAS malignas de la próstata, de los fibromas uterinos y del cáncer de mama metastásico.
Descriptor Portuguese: Gosserrelina
Descriptor French: Goséréline
Entry term(s): Acetate, Goserelin
Goserelin Acetate
ICI 118630
ICI-118630
ICI118630
Zoladex
Tree number(s): D06.472.699.327.740.320.340
D12.644.400.400.740.320.340
D12.644.456.460.315
D12.644.548.365.740.320.340
D12.776.631.650.405.740.320.340
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017273
Scope note: A synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE. Goserelin is used in treatments of malignant NEOPLASMS of the prostate, uterine fibromas, and metastatic breast cancer.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Hormonal
Registry Number: 0F65R8P09N
CAS Type 1 Name: Luteinizing hormone-releasing factor (pig), 6-(O-(1,1-dimethylethyl)-D-serine)-10-deglycinamide-, 2-(aminocarbonyl)hydrazide
Previous Indexing: Buserelin/analogs & derivatives (1984-1992)
Gonadorelin/analogs & derivatives (1979-1984)
Public MeSH Note: 93; ICI 118630 was indexed under BUSERELIN/analogs & derivatives 1984-92 & GONADORELIN/analogs & derivatives 1979-84
Online Note: use GOSERELIN (NM) to search ICI 118630 1980-92
History Note: 93; was ICI 118630 (NM) 1979-92
DeCS ID: 30707
Unique ID: D017273
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/19
Revision Date: 2015/11/23
Goserelin - Preferred
Concept UI M0026217
Scope note A synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE. Goserelin is used in treatments of malignant NEOPLASMS of the prostate, uterine fibromas, and metastatic breast cancer.
Preferred term Goserelin
ICI-118630 - Narrower
Concept UI M0373292
Preferred term ICI-118630
Entry term(s) ICI 118630
ICI118630
Zoladex - Narrower
Concept UI M0026218
Preferred term Zoladex
Goserelin Acetate - Narrower
Concept UI M0373293
Preferred term Goserelin Acetate
Entry term(s) Acetate, Goserelin



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