| Descriptor English: | Acitretin | ||||||
| Descriptor Spanish: | 
                                Acitretina                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Acitretina | ||||||
| Descriptor French: | Acitrétine | ||||||
| Entry term(s): | 
                                    13-cis-Acitretin Acitretin, (Z,E,E,E)-Isomer Etretin Isoacitretin Isoetretin Neotigason Ro 10-1670 Ro 101670 Ro 13-7652 Ro 137652 Ro-10-1670 Ro-13-7652 Ro101670 Ro137652 Soriatane  | 
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| Tree number(s): | 
                                        D02.455.326.271.665.202.495.050 D02.455.849.131.495.050 D23.767.261.700.050  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017255 | ||||||
| Scope note: | An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of ETRETINATE with the advantage of a much shorter half-life when compared with etretinate. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Keratolytic Agents | 
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| Registry Number: | LCH760E9T7 | ||||||
| CAS Type 1 Name: | 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (all-E)- | ||||||
| Previous Indexing: | 
                                                Tretinoin/analogs & derivatives (1977-1992) | 
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| Public MeSH Note: | 93; ACITRETIN was indexed under TRETINOIN/analogs & derivatives 1977-92 | 
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| Online Note: | use ACITRETIN (NM) to search ACITRETIN 1980-92 | 
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| History Note: | 93; was ACITRETIN (NM) 1977-91 | 
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| DeCS ID: | 30874 | ||||||
| Unique ID: | D017255 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1993/01/01 | ||||||
| Date of Entry: | 1992/05/07 | ||||||
| Revision Date: | 2017/02/24 | 
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                                        CHEMICALS AND DRUGS
 
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors 
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                                                             | 
                                
                        
                                                                    
                        Acitretin                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Isoacitretin                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                                                                    
                        Isoetretin                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                                                                    
                        Ro 10-1670                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        13-cis-Acitretin                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                                                                    
                        Neotigason                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Soriatane                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Acitretin, (Z,E,E,E)-Isomer                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                                                                    
                        Ro-13-7652                                            
                                        - Related but not broader or narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0026177 | 
                                
| Scope note | An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of ETRETINATE with the advantage of a much shorter half-life when compared with etretinate. | 
| Preferred term | Acitretin | 
| Entry term(s) | 
                                        
                                                                                            Etretin                                                 | 
                                
| Concept UI | 
                                        
                                        M0026181 | 
                                
| Preferred term | Isoacitretin | 
| Concept UI | 
                                        
                                        M0026179 | 
                                
| Preferred term | Isoetretin | 
| Concept UI | 
                                        
                                        M0351967 | 
                                
| Preferred term | Ro 10-1670 | 
| Entry term(s) | 
                                        
                                                                                            Ro 101670                                                 Ro-10-1670 Ro101670  | 
                                
| Concept UI | 
                                        
                                        M0026178 | 
                                
| Preferred term | 13-cis-Acitretin | 
| Concept UI | 
                                        
                                        M000625559 | 
                                
| Preferred term | Neotigason | 
| Concept UI | 
                                        
                                        M0026182 | 
                                
| Preferred term | Soriatane | 
| Concept UI | 
                                        
                                        M0329348 | 
                                
| Preferred term | Acitretin, (Z,E,E,E)-Isomer | 
| Concept UI | 
                                        
                                        M0026180 | 
                                
| Preferred term | Ro-13-7652 | 
| Entry term(s) | 
                                        
                                                                                            Ro 13-7652                                                 Ro 137652 Ro137652  | 
                                
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