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Descriptor English: Lymphocyte Culture Test, Mixed
Descriptor Spanish: Prueba de Cultivo Mixto de Linfocitos
Descriptor prueba de cultivo mixto de linfocitos
Entry term(s) prueba de cultivo mixto de leucocitos
reacción linfocítica mixta
test de cultivo mixto de leucocitos
test de cultivo mixto de linfocitos
Scope note: Medida de histocompatibilidad en el locus HL-A. Se mezclan en cultivo los linfocitos de la sangre periférica de dos individuos durante varios días. Los linfocitos de individuos incompatibles se estimularán mutuamente y proliferarán significativamente (medido por la captación de timidina tritiada), mientras que los que pertenecen a individuos compatibles no lo harán. En la prueba de CML unidireccional se inactivan los linfocitos de uno de los individuos (usualmente por tratamiento con MITOMICINA o irradiación) permitiendo así que, en respuesta a los antígenos de histocompatibilidad extraños, prolifere sólo la población de células no tratadas.
Descriptor Portuguese: Teste de Cultura Mista de Linfócitos
Descriptor French: Test de culture lymphocytaire mixte
Entry term(s): Leukocyte Culture Test, Mixed
Leukocyte Reaction, Mixed
Leukocyte Reactions, Mixed
Lymphocyte Reaction, Mixed
Lymphocyte Reactions, Mixed
Mixed Leukocyte Culture Test
Mixed Leukocyte Reaction
Mixed Leukocyte Reactions
Mixed Lymphocyte Culture Test
Mixed Lymphocyte Reaction
Mixed Lymphocyte Reactions
Tree number(s): E01.370.225.812.385.475
E05.200.812.385.475
E05.478.594.385.429
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007959
Scope note: Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
Annotation: NIM
Allowable Qualifiers: AE adverse effects
CL classification
EC economics
ES ethics
HI history
IS instrumentation
MO mortality
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Previous Indexing: Histocompatibility Testing (1968-1972)
Leukocytes (1966-1972)
Public MeSH Note: 93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92
Online Note: use LYMPHOCYTE CULTURE TEST, MIXED to search LEUKOCYTE CULTURE TEST, MIXED 1973-92
History Note: 93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92
DeCS ID: 30911
Unique ID: D007959
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2011/06/24
Lymphocyte Culture Test, Mixed - Preferred
Concept UI M0012408
Scope note Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
Preferred term Lymphocyte Culture Test, Mixed
Entry term(s) Leukocyte Culture Test, Mixed
Leukocyte Reaction, Mixed
Leukocyte Reactions, Mixed
Lymphocyte Reaction, Mixed
Lymphocyte Reactions, Mixed
Mixed Leukocyte Culture Test
Mixed Leukocyte Reaction
Mixed Leukocyte Reactions
Mixed Lymphocyte Culture Test
Mixed Lymphocyte Reaction
Mixed Lymphocyte Reactions



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